Evidence map›Paper›PMID 37509147›Full record

ArticleBiomolecules2023

Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells.

Hakki Gurhan, Marek Bajtoš, Frank Barnes

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hakki GurhanDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, 1111 Engineering Dr 425 UCB, Boulder, CO 80309, USA.ORCID 0000-0002-1412-3891
Marek BajtošDepartment of Electromagnetic and Biomedical Engineering, University of Žilina, Univerzitná 8215/1, 010 26 Žilina, Slovakia.ORCID 0000-0003-0817-1413
Frank BarnesDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, 1111 Engineering Dr 425 UCB, Boulder, CO 80309, USA.
University of Colorado Boulder · USUniversity of Žilina · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last few decades, evidence has surfaced that weak radiofrequency (RF) fields can influence biological systems. This work aims to improve our understanding of how externally applied weak RF fields alter concentrations of chemical parameters that characterize oxidative stress. We conducted a series of experiments to investigate the effects of applying weak RF magnetic fields within the 3-5 MHz region on mitochondrial respiration in both human fibrosarcoma and fibroblast cells over a period of four days. Our experimental data show that RF fields between 3 and 5 MHz were able to change the modulation of mitochondrial signaling by changing the cell growth, mitochondrial mass, and oxidative stress. Exposure to RF fields at 4.2 MHz significantly increased the mitochondrial mass and oxidative stress in fibrosarcoma cells. There are substantial concerns that extended exposure to weak RF fields can lead to health effects. The ability to control these parameters by external magnetic fields may have important clinical implications.

Indexed as

FibrosarcomaOxidative StressFibroblastsHumansMitochondriaRadio Wavescell deathcell growthiron sulphur clustersmitochondrial massoxidative stressradical pair mechanismweak RF fields

Identifiers

PMID37509147
PMCPMC10377549
OpenAlexW4384203141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.