Evidence map›Paper›PMID 37509079›Full record

ArticleBiomolecules2023

Unraveling the Transport Properties of RONS across Nitro-Oxidized Membranes.

Davronjon Abduvokhidov, Maksudbek Yusupov, Aamir Shahzad, Pankaj Attri, Masaharu Shiratani, Maria C Oliveira, Jamoliddin Razzokov

Abstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Davronjon AbduvokhidovInstitute of Fundamental and Applied Research, National Research University TIIAME, Kori Niyoziy 39, Tashkent 100000, Uzbekistan.ORCID 0009-0007-3695-0437
Maksudbek YusupovR&D Center, New Uzbekistan University, Mustaqillik Avenue 54, Tashkent 100007, Uzbekistan.ORCID 0000-0003-4591-858X
Aamir ShahzadModeling and Simulation Laboratory, Department of Physics, Government College University Faisalabad (GCUF), Allama Iqbal Road, Faisalabad 38040, Pakistan.
Pankaj AttriCenter of Plasma Nano-Interface Engineering, Kyushu University, Fukuoka 819-0395, Japan.ORCID 0000-0002-5036-7877
Masaharu ShirataniCenter of Plasma Nano-Interface Engineering, Kyushu University, Fukuoka 819-0395, Japan.ORCID 0000-0002-4103-3939
Maria C OliveiraResearch Group PLASMANT, Department of Chemistry, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.ORCID 0000-0003-4311-7906
Jamoliddin RazzokovInstitute of Fundamental and Applied Research, National Research University TIIAME, Kori Niyoziy 39, Tashkent 100000, Uzbekistan.ORCID 0000-0002-3098-0797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential of cold atmospheric plasma (CAP) in biomedical applications has received significant interest, due to its ability to generate reactive oxygen and nitrogen species (RONS). Upon exposure to living cells, CAP triggers alterations in various cellular components, such as the cell membrane. However, the permeation of RONS across nitrated and oxidized membranes remains understudied. To address this gap, we conducted molecular dynamics simulations, to investigate the permeation capabilities of RONS across modified cell membranes. This computational study investigated the translocation processes of less hydrophilic and hydrophilic RONS across the phospholipid bilayer (PLB), with various degrees of oxidation and nitration, and elucidated the impact of RONS on PLB permeability. The simulation results showed that less hydrophilic species, i.e., NO, NO

Indexed as

Hydrogen PeroxideOxygenCell MembraneMolecular Dynamics SimulationPhospholipidsReactive Nitrogen SpeciesReactive Oxygen SpeciesHydrogen PeroxideOxygenPhospholipidsReactive Nitrogen SpeciesReactive Oxygen Speciescold atmospheric plasmafree energy profilemolecular dynamicsnitro-oxidized membranesreactive oxygen and nitrogen species

Identifiers

PMID37509079
PMCPMC10377474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.