Evidence map›Paper›PMID 37508976›Full record

ArticleBrain sciences2023

The Processing of Audiovisual Speech Is Linked with Vocabulary in Autistic and Nonautistic Children: An ERP Study.

Kacie Dunham-Carr, Jacob I Feldman, David M Simon, Sarah R Edmunds, Alexander Tu, Wayne Kuang, Julie G Conrad, Pooja Santapuram, Mark T Wallace, Tiffany G Woynaroski

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Kacie Dunham-CarrVanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0002-4434-1056
Jacob I FeldmanFrist Center for Autism and Innovation, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0002-5723-5834
David M SimonVanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232, USA.
Sarah R EdmundsDepartment of Psychology, University of Washington, Seattle, WA 98195, USA.
Alexander TuNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0003-2387-1688
Wayne KuangNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0003-3155-4121
Julie G ConradNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN 37232, USA.
Pooja SantapuramNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0002-8284-9547
Mark T WallaceVanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0002-0166-906X
Tiffany G WoynaroskiVanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232, USA.ORCID 0000-0001-6513-1181
Vanderbilt University · USIllinois College · USUniversity of Hawaiʻi at Mānoa · USUniversity of South Carolina · USUniversity of Southern California · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
NRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R01DC020186 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tiffany Woynaroski · 2022 to 2026
$3.2M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)KL2TR000446 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$2.8M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R21DC016144 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WOYNAROSKI, TIFFANY · 2017 to 2019
$474k
Looking to and Processing of Audiovisual Speech in Infants at Risk for AutismF31DC020129 · NIDCD · VANDERBILT UNIVERSITY · PI DUNHAM-CARR, KACIE · 2021 to 2024
$89k
The Role of Vocal Complexity in Expressive Language Outcome: Developmental Course and Intervention Effects in Toddlers at Risk for ASD and Language ImpairmentF31DC015696 · NIDCD · UNIVERSITY OF WASHINGTON · PI EDMUNDS, SARAH R. · 2016 to 2017
$83k
NCATS NIH HHS KL2 TR000446NCATS NIH HHS KL2TR000446NCATS NIH HHS TL1 TR002244NCATS NIH HHS TL1TR002244NICHD NIH HHS P50 HD103537NICHD NIH HHS U54 HD083211NIDCD NIH HHS F31DC015696NIDCD NIH HHS F31 DC020129NIDCD NIH HHS F31DC020129NIDCD NIH HHS R01 DC020186NIDCD NIH HHS R01DC020186NIDCD NIH HHS R21 DC016144NIDCD NIH HHS R21DC016144
6 · The paper itself

Abstract

Explaining individual differences in vocabulary in autism is critical, as understanding and using words to communicate are key predictors of long-term outcomes for autistic individuals. Differences in audiovisual speech processing may explain variability in vocabulary in autism. The efficiency of audiovisual speech processing can be indexed via amplitude suppression, wherein the amplitude of the event-related potential (ERP) is reduced at the P2 component in response to audiovisual speech compared to auditory-only speech. This study used electroencephalography (EEG) to measure P2 amplitudes in response to auditory-only and audiovisual speech and norm-referenced, standardized assessments to measure vocabulary in 25 autistic and 25 nonautistic children to determine whether amplitude suppression (a) differs or (b) explains variability in vocabulary in autistic and nonautistic children. A series of regression analyses evaluated associations between amplitude suppression and vocabulary scores. Both groups demonstrated P2 amplitude suppression, on average, in response to audiovisual speech relative to auditory-only speech. Between-group differences in mean amplitude suppression were nonsignificant. Individual differences in amplitude suppression were positively associated with expressive vocabulary through receptive vocabulary, as evidenced by a significant indirect effect observed across groups. The results suggest that efficiency of audiovisual speech processing may explain variance in vocabulary in autism.

Indexed as

audiovisualautismEEGlanguagesensoryspeechvocabulary

Identifiers

PMID37508976
PMCPMC10377472
OpenAlexW4383723883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.