Evidence map›Paper›PMID 37508962›Full record

ReviewBrain sciences2023

Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders.

Gonçalo Cotovio, Fabiana Ventura, Daniel Rodrigues da Silva, Patrícia Pereira, Albino J Oliveira-Maia

Erratum issued Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06490965 (Improving Obsessive-compulsive Disorder Treatments), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06490965 narecruitingnot on this mapstarted 2024, after this paper: background citation

Improving Obsessive-compulsive Disorder Treatments: from Lesions to Neuromodulation Targets

TypeinterventionalSponsorFundacao ChampalimaudRan2024 to 2026Enrolled32ConditionsObsessive-Compulsive DisorderArmsRepetitive Transcranial Magnetic Stimulation, Neuronavigation, Magnetic Resonance Imaging
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  7. Article
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  9. rTMS Therapy for Eating Disorders: Scoping Review on Efficacy, Safety, Stimulation Parameters and Study Subjects.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Review
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  11. Article
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  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gonçalo CotovioChampalimaud Research and Clinical Centre, Champalimaud Foundation, 1400-038 Lisbon, Portugal.ORCID 0000-0002-1267-645X
Fabiana VenturaChampalimaud Research and Clinical Centre, Champalimaud Foundation, 1400-038 Lisbon, Portugal.ORCID 0000-0001-9171-0291
Daniel Rodrigues da SilvaChampalimaud Research and Clinical Centre, Champalimaud Foundation, 1400-038 Lisbon, Portugal.
Patrícia PereiraChampalimaud Research and Clinical Centre, Champalimaud Foundation, 1400-038 Lisbon, Portugal.
Albino J Oliveira-MaiaChampalimaud Research and Clinical Centre, Champalimaud Foundation, 1400-038 Lisbon, Portugal.ORCID 0000-0001-5071-3007
Champalimaud Foundation · PT

Funding

European Research Council grant agreement no. 950357
6 · The paper itself

Abstract

Non-invasive brain stimulation techniques (NIBS) have been widely used in both clinical and research contexts in neuropsychiatry. They are safe and well-tolerated, making NIBS an interesting option for application in different settings. Transcranial magnetic stimulation (TMS) is one of these strategies. It uses electromagnetic pulses for focal modulate ion of neuronal activity in brain cortical regions. When pulses are applied repeatedly (repetitive transcranial magnetic stimulation-rTMS), they are thought to induce long-lasting neuroplastic effects, proposed to be a therapeutic mechanism for rTMS, with efficacy and safety initially demonstrated for treatment-resistant depression (TRD). Since then, many rTMS treatment protocols emerged for other difficult to treat psychiatric conditions. Moreover, multiple clinical studies, including large multi-center trials and several meta-analyses, have confirmed its clinical efficacy in different neuropsychiatric disorders, resulting in evidence-based guidelines and recommendations. Currently, rTMS is cleared by multiple regulatory agencies for the treatment of TRD, depression with comorbid anxiety disorders, obsessive compulsive disorder, and substance use disorders, such as smoking cessation. Importantly, current research supports the potential future use of rTMS for other psychiatric syndromes, including the negative symptoms of schizophrenia and post-traumatic stress disorder. More precise knowledge of formal indications for rTMS therapeutic use in psychiatry is critical to enhance clinical decision making in this area.

Indexed as

approvalclearancepsychiatric disordersregulatory agenciestranscranial magnetic stimulation

Identifiers

PMID37508962
PMCPMC10377201
OpenAlexW4383344968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.