Evidence map›Paper›PMID 37508881›Full record

ArticleBioengineering (Basel, Switzerland)2023

Hydrogel-Impregnated Self-Oxygenating Electrospun Scaffolds for Bone Tissue Engineering.

Robin Augustine, Vasilios K Nikolopoulos, Gulden Camci-Unal

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  7. Harnessing the Power ofInternational journal of nanomedicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Robin AugustineDepartment of Chemical Engineering, University of Massachusetts, Lowell, MA 01854, USA.
Vasilios K NikolopoulosDepartment of Chemical Engineering, University of Massachusetts, Lowell, MA 01854, USA.ORCID 0000-0002-0384-0713
Gulden Camci-UnalDepartment of Chemical Engineering, University of Massachusetts, Lowell, MA 01854, USA.ORCID 0000-0003-4258-844X
University of Massachusetts Lowell · US

Funding

Scaffolds with high oxygen content for mineralizationR01DE030129 · NIDCR · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CAMCI-UNAL, GULDEN · 2021 to 2025
$2.0M
NIDCR NIH HHS R01 DE030129NIH HHS R01DE030129
6 · The paper itself

Abstract

Bone defects resulting from trauma, disease, or aging present significant challenges in the clinic. Although biomaterial scaffolds for bone-tissue engineering have shown promising results, challenges remain, including the need for adequate mechanical strength and suitable bioactive agents within scaffolds to promote bone formation. Oxygen is a critical factor for successful bone formation, and low oxygen tension inhibits it. In this study, we developed gelatin methacryloyl (GelMA) hydrogel-impregnated electrospun polycaprolactone (PCL) scaffolds that can release oxygen over 3 weeks. We investigated the potential of composite scaffolds for cell survival in bone-tissue engineering. Our results showed that the addition of an increased amount of CaO

Indexed as

bone tissue engineeringCaO2GelMAoxygen-generating materialsPCLscaffolds

Identifiers

PMID37508881
PMCPMC10376476
OpenAlexW4384931115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.