ArticleBioengineering (Basel, Switzerland)2023
Impact of Aspiration Percutaneous Vertebroplasty in Reducing Bone Cement Leakage and Enhancing Distribution-An Ex Vivo Study in Goat Vertebrae.
Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 3 citations in OpenAlex.
- Percutaneous Vertebroplasty for Painful Osteoporotic Vertebral Compression Fractures: A Retrospective Comparative Study of a Negative Pressure-Guided Technique.Orthopaedic surgery · 2026Article
- Safety and efficacy of decompressed vertebroplasty in reducing pulmonary fat embolism: a proof-of-mechanism study in a sheep model.North American Spine Society journal · 2026Article
- Efficacy of polymethyl methacrylate combined with calcium phosphate cement in percutaneous vertebroplasty for postmenopausal women with osteoporotic thoracolumbar compression fractures.Journal of orthopaedic surgery and research · 2026Article
- Intraoperative Suction-Assisted Kyphoplasty for Immediate Removal of Posterior PMMA Extravasation in Decompressed Vertebral Compression Fractures.Journal of clinical medicine · 2026Article
- Preoperative CT-Based Planning for Unilateral Pedicle Approach PVP Reduces Cement Leakage and Improves Radiological Outcomes in Osteoporotic Vertebral Compression Fractures: A Retrospective Cohort Study.Journal of pain research · 2026Article
- Clinical study of separation surgery combined with intraoperative vertebroplasty andWorld journal of surgical oncology · 2025Article
- Article
- Assessment of Cement Leakage in Decompressed Percutaneous Kyphoplasty.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Osteoporosis-induced vertebral compression fracture (OVCF) occurs commonly in people over the age of 50, especially among menopausal women. Besides conservative therapy, minimally invasive percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) have been widely used in clinical treatment and achieved good efficacy. However, the leakage of bone cement (CL) during vertebroplasty (PV) is a major risk that can cause (serious) complications such as compression of the spinal cord, pulmonary embolism, or even paraplegia. In this study, we introduced a new aspiration technique with standard PV procedures (APV) to ameliorate the risk of leakage with quantitative verifications of its effectiveness. APV intends to create a differential pressure to guide the direction of cement flow within the vertebrae. To test this technique, Nubian goats' ex vivo vertebral bodies (VBs) were used to simulate the PV surgical process in humans. Results show that the proposed APV has a lower leakage rate of 13% compared to the 53% of conventional PV. Additionally, the APV approach achieves more uniform cement distribution via the 9-score method with a value of 7 ± 1.30 in contrast to 4 ± 1.78 by conventional PV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.