Evidence map›Paper›PMID 37508615›Full record

ArticleChildren (Basel, Switzerland)2023

Incomplete Exhalation during Resuscitation-Theoretical Review and Examples from Ventilation of Newborn Term Infants.

Thomas Drevhammar, Peder Aleksander Bjorland, Joanna Haynes, Joar Eilevstjønn, Murray Hinder, Mark Tracy, Siren Irene Rettedal, Hege Langli Ersdal

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Thomas DrevhammarDepartment of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0002-4038-2221
Peder Aleksander BjorlandDepartment of Paediatrics, Stavanger University Hospital, 4019 Stavanger, Norway.
Joanna HaynesDepartment of Anaesthesia, Stavanger University Hospital, 4019 Stavanger, Norway.
Joar EilevstjønnLaerdal Medical, Strategic Research Department, 4007 Stavanger, Norway.ORCID 0000-0002-4607-2689
Murray HinderDepartment of Paediatrics and Child Health, Sydney University, Westmead, Sydney, NSW 2006, Australia.ORCID 0000-0002-9179-316X
Mark TracyDepartment of Paediatrics and Child Health, Sydney University, Westmead, Sydney, NSW 2006, Australia.ORCID 0000-0001-5648-468X
Siren Irene RettedalDepartment of Paediatrics, Stavanger University Hospital, 4019 Stavanger, Norway.ORCID 0000-0002-4305-141X
Hege Langli ErsdalDepartment of Anaesthesia, Stavanger University Hospital, 4019 Stavanger, Norway.
Stavanger University Hospital · NOThe University of Sydney · AUKarolinska Institutet · SELaerdal (Norway) · NO

Funding

Region Jämtland Härjedalen Senior research position
6 · The paper itself

Abstract

backgroundNewborn resuscitation guidelines recommend positive pressure ventilation (PPV) for newborns who do not establish effective spontaneous breathing after birth. T-piece resuscitator systems are commonly used in high-resource settings and can additionally provide positive end-expiratory pressure (PEEP). Short expiratory time, high resistance, rapid dynamic changes in lung compliance and large tidal volumes increase the possibility of incomplete exhalation. Previous publications indicate that this may occur during newborn resuscitation. Our aim was to study examples of incomplete exhalations in term newborn resuscitation and discuss these against the theoretical background.

methodsExamples of flow and pressure data from respiratory function monitors (RFM) were selected from 129 term newborns who received PPV using a T-piece resuscitator. RFM data were not presented to the user during resuscitation.

resultsExamples of incomplete exhalation with higher-than-set PEEP-levels were present in the recordings with visual correlation to factors affecting time needed to complete exhalation.

conclusionsIncomplete exhalation and the relationship to expiratory time constants have been well described theoretically. We documented examples of incomplete exhalations with increased PEEP-levels during resuscitation of term newborns. We conclude that RFM data from resuscitations can be reviewed for this purpose and that incomplete exhalations should be further explored, as the clinical benefit or risk of harm are not known.

Indexed as

infantintrinsicnewbornpositive end-expiratory pressurepositive pressure ventilationresuscitation

Identifiers

PMID37508615
PMCPMC10377906
OpenAlexW4382584286

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.