Evidence map›Paper›PMID 37508583›Full record

ArticleCells2023

Intercorrelation of Molecular Biomarkers and Clinical Phenotype Measures in Fragile X Syndrome.

Ramkumar Aishworiya, Mei-Hung Chi, Marwa Zafarullah, Guadalupe Mendoza, Matthew Dominic Ponzini, Kyoungmi Kim, Hazel Maridith Barlahan Biag, Angela John Thurman, Leonard Abbeduto, David Hessl and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. In Utero Alcohol and Unsuitable Home Environmental Exposure Combined withInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Ramkumar AishworiyaMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0002-5749-1248
Mei-Hung ChiMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Marwa ZafarullahDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, CA 95817, USA.ORCID 0000-0003-1856-0535
Guadalupe MendozaDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, CA 95817, USA.
Matthew Dominic PonziniMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Kyoungmi KimMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Hazel Maridith Barlahan BiagMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Angela John ThurmanMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Leonard AbbedutoMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0002-2311-7194
David HesslMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Jamie Leah RandolDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, CA 95817, USA.
Francois V BolducDepartment of Pediatrics, Department of Medical Genetics, Women and Children Health Research Institute, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Sebastien JacquemontCHU Sainte-Justine Research Center, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Sarah LippéCHU Sainte-Justine Research Center, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Paul HagermanMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
Randi HagermanMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0001-5029-8448
Andrea SchneiderMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0002-4674-7244
Flora TassoneMIND Institute, University of California Davis Medical Center, Sacramento, CA 95817, USA.
University of California Davis Medical Center · USUniversity of California, Davis · USCentre Hospitalier Universitaire Sainte-Justine · CANational Cheng Kung University Hospital · TWNational University of Singapore · SGUniversity of Alberta · CA

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
NICHD NIH HHS NICHD P50 HD103526NICHD NIH HHS P50 HD103526
6 · The paper itself

Abstract

This study contributes to a greater understanding of the utility of molecular biomarkers to identify clinical phenotypes of fragile X syndrome (FXS). Correlations of baseline clinical trial data (molecular measures-

Indexed as

Fragile X SyndromeBiomarkersFragile X Messenger Ribonucleoprotein 1HumansPhenotypeRNA, MessengerBiomarkersFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1RNA, Messengerclinical trialFMR1 mRNAFMRPfragile X syndromeMMP9outcome measures

Identifiers

PMID37508583
PMCPMC10377864
OpenAlexW4385255337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.