Evidence map›Paper›PMID 37508507›Full record

ArticleCells2023

Distinct Organotypic Platforms Modulate Rainbow Trout (

Nicole Verdile, Federica Camin, Radmila Pavlovic, Rolando Pasquariello, Milda Stuknytė, Ivano De Noni, Tiziana A L Brevini, Fulvio Gandolfi

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nicole VerdileDepartment of Agricultural and Environmental Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0001-7244-9577
Federica CaminDepartment of Agricultural and Environmental Sciences, University of Milan, 20133 Milan, Italy.
Radmila PavlovicDepartment of Veterinary Medicine and Animal Sciences, University of Milan, 26900 Lodi, Italy.ORCID 0000-0002-2128-4589
Rolando PasquarielloDepartment of Agricultural and Environmental Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0003-3191-7009
Milda StuknytėUnitech COSPECT-University Technological Platform, University of Milan, 20133 Milan, Italy.ORCID 0000-0003-2352-8628
Ivano De NoniDepartment of Food, Environmental and Nutritional Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0003-1281-7053
Tiziana A L BreviniDepartment of Veterinary Medicine and Animal Sciences, University of Milan, 26900 Lodi, Italy.ORCID 0000-0002-0428-3621
Fulvio GandolfiDepartment of Agricultural and Environmental Sciences, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-3246-2985
University of Milan · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vitro organotypic cell-based intestinal platforms, able to faithfully recapitulate the complex functions of the organ in vivo, would be a great support to search for more sustainable feed ingredients in aquaculture. We previously demonstrated that proliferation or differentiation of rainbow trout intestinal cell lines is dictated by the culture environment. The aim of the present work was to develop a culture platform that can efficiently promote cell differentiation into mature enterocytes. We compared four options, seeding the RTpiMI cell line derived from the proximal intestine on (1) polyethylene terephthalate (PET) culture inserts ThinCert™ (TC), (2) TC coated with the solubilized basement membrane matrix Matrigel

Indexed as

Oncorhynchus mykissAnimalsCell LineIntestinal MucosaIntestinesMicrovilliaquaculturecell differentiationenterocytesintestinal cellsin vitro intestineorganoidsorganotypic culturerainbow troutsustainable feed

Identifiers

PMID37508507
PMCPMC10377977
OpenAlexW4384340993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.