Evidence map›Paper›PMID 37508494›Full record

ArticleCells2023

Structural and Kinetic Characterization of the SpeG Spermidine/Spermine

Sofiya Tsimbalyuk, Aleksander Shornikov, Parul Srivastava, Van Thi Bich Le, Imani Warren, Yogesh B Khandokar, Misty L Kuhn, Jade K Forwood

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Antibiotics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sofiya TsimbalyukSchool of Dentistry and Medical Sciences, Charles Sturt University, Boorooma Street, Wagga Wagga, NSW 2678, Australia.
Aleksander ShornikovDeparment of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.
Parul SrivastavaSchool of Dentistry and Medical Sciences, Charles Sturt University, Boorooma Street, Wagga Wagga, NSW 2678, Australia.
Van Thi Bich LeDeparment of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.
Imani WarrenDeparment of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.
Yogesh B KhandokarSchool of Dentistry and Medical Sciences, Charles Sturt University, Boorooma Street, Wagga Wagga, NSW 2678, Australia.ORCID 0000-0002-4630-8508
Misty L KuhnDeparment of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.ORCID 0000-0002-7951-9141
Jade K ForwoodSchool of Dentistry and Medical Sciences, Charles Sturt University, Boorooma Street, Wagga Wagga, NSW 2678, Australia.
Charles Sturt University · AUSan Francisco State University · US

Funding

Investigating the structure, function, and regulation of polyamine acetyltransferasesR35GM133506 · NIGMS · SAN FRANCISCO STATE UNIVERSITY · PI Misty Kuhn · 2019 to 2026
$2.9M
NIGMS NIH HHS R35 GM133506NIH HHS R35GM133506
6 · The paper itself

Abstract

Polyamines are simple yet critical molecules with diverse roles in numerous pathogenic and non-pathogenic organisms. Regulating polyamine concentrations affects the transcription and translation of genes and proteins important for cell growth, stress, and toxicity. One way polyamine concentrations are maintained within the cell is via spermidine/spermine

Indexed as

Methicillin-Resistant Staphylococcus aureusSpermidineAcetyltransferasesPolyaminesSpermineAcetyltransferasesPolyaminesSpermidineSpermineacetylationGcn5-related N-acetyltransferase (GNAT)MRSA USA300polyaminespermidine/spermine N-acetyltransferase (SSAT)Staphylococcus aureus

Identifiers

PMID37508494
PMCPMC10378331
OpenAlexW4384131425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.