Evidence map›Paper›PMID 37508398›Full record

ArticleBiology2023

Secretion of Interleukin 6 in Human Skeletal Muscle Cultures Depends on Ca

Blanca Calle-Ciborro, Teresa Espin-Jaime, Francisco J Santos, Ana Gomez-Martin, Isaac Jardin, Maria J Pozo, Juan A Rosado, Pedro J Camello, Cristina Camello-Almaraz

Open access · goldAbstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Blanca Calle-CiborroDepartment of Physiology, Instituto de Biomarcadores Patológicos Moleculares y Metabólicos, Universidad de Extremadura, 10003 Cáceres, Spain.
Teresa Espin-JaimeFaculty of Medicine, Hospital Universitario, Universidad de Extremadura, 06006 Badajoz, Spain.
Francisco J SantosHospital Universitario, 10004 Cáceres, Spain.
Ana Gomez-MartinDepartment of Nursing, Faculty of Nursing and Occupational Therapy, Universidad de Extremadura, 10003 Cáceres, Spain.
Isaac JardinDepartment of Physiology, Instituto de Biomarcadores Patológicos Moleculares y Metabólicos, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0003-4575-8264
Maria J PozoDepartment of Physiology, Instituto de Biomarcadores Patológicos Moleculares y Metabólicos, Universidad de Extremadura, 10003 Cáceres, Spain.
Juan A RosadoDepartment of Physiology, Instituto de Biomarcadores Patológicos Moleculares y Metabólicos, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0002-9749-2325
Pedro J CamelloDepartment of Physiology, Instituto de Biomarcadores Patológicos Moleculares y Metabólicos, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0001-5026-7166
Cristina Camello-AlmarazDepartment of Physiology, Instituto de Biomarcadores Patológicos Moleculares y Metabólicos, Universidad de Extremadura, 10003 Cáceres, Spain.
Universidad de Extremadura · ESComplejo Hospitalario de Cáceres · ES

Funding

JUNTA DE EXTREMADURA GR21095JUNTA DE EXTREMADURA IB18025
6 · The paper itself

Abstract

The systemic effects of physical activity are mediated by the release of IL-6 and other myokines from contracting muscle. Although the release of IL-6 from muscle has been extensively studied, the information on the cellular mechanisms is fragmentary and scarce, especially regarding the role of Ca

Indexed as

Ca2+ signalsIL-6intracellular calcium storesskeletal musclestore operated calcium channelsvoltage operated calcium channels

Identifiers

PMID37508398
PMCPMC10376320
OpenAlexW4383496034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.