Evidence map›Paper›PMID 37508208›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Simulation of Vancomycin Exposure Using Trough and Peak Levels Achieves the Target Area under the Steady-State Concentration-Time Curve in ICU Patients.

Yuta Ibe, Tomoyuki Ishigo, Satoshi Fujii, Satoshi Takahashi, Masahide Fukudo, Hideki Sato

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuta IbeDepartment of Pharmacy, Sapporo Medical University Hospital, Sapporo 060-8543, Japan.
Tomoyuki IshigoDepartment of Pharmacy, Sapporo Medical University Hospital, Sapporo 060-8543, Japan.ORCID 0000-0002-2689-5338
Satoshi FujiiDepartment of Pharmacy, Sapporo Medical University Hospital, Sapporo 060-8543, Japan.ORCID 0000-0002-0353-7933
Satoshi TakahashiDepartment of Infection Control and Laboratory Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan.ORCID 0000-0002-2121-1021
Masahide FukudoDepartment of Pharmacy, Sapporo Medical University Hospital, Sapporo 060-8543, Japan.ORCID 0000-0002-7703-7827
Hideki SatoDepartment of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Sapporo 006-8585, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic drug monitoring (TDM) of vancomycin (VCM) in critically ill patients often results in the estimated area being under the concentration-time curve (AUC) values that deviate from individual observations. In this study, we investigated the factors influencing the achievement of the target AUC of VCM at steady-state in critically ill patients. We retrospectively collected data from patients treated with VCM in an intensive care unit (ICU). Multivariate analysis was used to adjust for significant factors with

Indexed as

area under the concentration–time curvecritically ill patientsintensive care unittherapeutic drug monitoringvancomycin

Identifiers

PMID37508208
PMCPMC10376485

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.