Evidence map›Paper›PMID 37508040›Full record

ArticleAnimals : an open access journal from MDPI2023

Comparative Label-Free Liquid Chromatography-Mass Spectrometry Milk Proteomic Profiles Highlight Putative Differences between the Autochthon Teramana and Saanen Goat Breeds.

Alessio Di Luca, Francesca Bennato, Andrea Ianni, Lisa Grotta, Michael Henry, Paula Meleady, Giuseppe Martino

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alessio Di LucaDepartment of Bioscience and Technology for Food Agro-Food and Environmental Technology, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0003-4988-6407
Francesca BennatoDepartment of Bioscience and Technology for Food Agro-Food and Environmental Technology, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0001-9030-4881
Andrea IanniDepartment of Bioscience and Technology for Food Agro-Food and Environmental Technology, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0003-3102-6804
Lisa GrottaDepartment of Bioscience and Technology for Food Agro-Food and Environmental Technology, University of Teramo, 64100 Teramo, Italy.
Michael HenryNational Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Dublin, Ireland.
Paula MeleadyNational Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Dublin, Ireland.
Giuseppe MartinoDepartment of Bioscience and Technology for Food Agro-Food and Environmental Technology, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0002-7878-9318
University of Teramo · ITDublin City University · IE

Funding

European Union - Next Generation EU. Project Title: Innovation, digitalization and sus-tainability for the diffused economy in Central Italy - VITALITY Project Code: ECS00000041; Project CUP: C43C22000380007
6 · The paper itself

Abstract

Goat's milk is an excellent source of nutrients, with greater benefits compared to cow's milk. Limited information is available on autochthon goat breeds, which are important for biodiversity preservation. In this study, the aim of using label-free quantification was to investigate the milk proteome of two goat breeds, the autochthon Teramana and Saanen breeds, which are commonly used by the industry. Utilising label-free proteomic analysis, 749 and 666 proteins, respectively were identified and quantified from the Teramana and Saanen goat milk. Moreover, utilising statistical analysis, 29 proteins were able to discriminate the two goat breeds, with many of the identified proteins involved in complement and coagulation cascades. This work enhances our understanding of the goat milk proteome and shows differences between the two breeds, leading to an important contribution toward a more detailed molecular-view of this unique substrate. Additionally, charactersation of the milk proteins can help in guiding genetic improvements in the goat herds, and thus increasing its use in human nutrition.

Indexed as

label-free LC–MSmilkproteomicssaanen goatteramana goat

Identifiers

PMID37508040
PMCPMC10376190
OpenAlexW4383878341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.