Evidence map›Paper›PMID 37507999›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Pepper Fruit Extracts Show Anti-Proliferative Activity against Tumor Cells Altering Their NADPH-Generating Dehydrogenase and Catalase Profiles.

Marta Rodríguez-Ruiz, María C Ramos, María J Campos, Inmaculada Díaz-Sánchez, Bastien Cautain, Thomas A Mackenzie, Francisca Vicente, Francisco J Corpas, José M Palma

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Capsaicin: a spicy way in liver disease.Frontiers in pharmacology · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Marta Rodríguez-RuizGroup of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín (Spanish National Research Council, CSIC), 18008 Granada, Spain.
María C RamosDepartment Screening & Target Validation, Fundación MEDINA, 18016 Granada, Spain.ORCID 0000-0002-3674-615X
María J CamposGroup of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín (Spanish National Research Council, CSIC), 18008 Granada, Spain.
Inmaculada Díaz-SánchezGroup of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín (Spanish National Research Council, CSIC), 18008 Granada, Spain.
Bastien CautainEvotec, University Paul Sabatier Toulouse III, 31100 Toulouse, France.
Thomas A MackenzieDepartment Screening & Target Validation, Fundación MEDINA, 18016 Granada, Spain.
Francisca VicenteDepartment Screening & Target Validation, Fundación MEDINA, 18016 Granada, Spain.
Francisco J CorpasGroup of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín (Spanish National Research Council, CSIC), 18008 Granada, Spain.ORCID 0000-0002-1814-9212
José M PalmaGroup of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín (Spanish National Research Council, CSIC), 18008 Granada, Spain.ORCID 0000-0001-6673-3571
Consejo Superior de Investigaciones Científicas · ESFundación Medina · ESUniversité Toulouse III - Paul Sabatier · FR

Funding

Ministry of Science and Innovation, Spain PID2019-103924GB-I00Ministry of Science and Innovation, Spain PIN-0474-2016Regional Government of Andalusia P18-FR-1359
6 · The paper itself

Abstract

Cancer is considered one of the main causes of human death worldwide, being characterized by an alteration of the oxidative metabolism. Many natural compounds from plant origin with anti-tumor attributes have been described. Among them, capsaicin, which is the molecule responsible for the pungency in hot pepper fruits, has been reported to show antioxidant, anti-inflammatory, and analgesic activities, as well as anti-proliferative properties against cancer. Thus, in this work, the potential anti-proliferative activity of pepper (

Indexed as

antioxidantscapsaicincatalasehepatomahot pepperhydrogen peroxideNADPHnitric oxidepancreas

Identifiers

PMID37507999
PMCPMC10376568
OpenAlexW4384931488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.