Evidence map›Paper›PMID 37507944›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Rising Influence of Nanotechnology in Addressing Oxidative Stress-Related Liver Disorders.

Sathiyamoorthy Padmanaban, Durgasruthi Pully, Antony V Samrot, Vijayakumar Gosu, Nanthini Sadasivam, In-Kyu Park, Kamalakannan Radhakrishnan, Don-Kyu Kim

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Green Synthesis of Silver Nanoparticles UsingCurrent pharmaceutical biotechnology · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sathiyamoorthy PadmanabanDepartment of Biomedical Sciences and BioMedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
Durgasruthi PullyBiochemistry and Biotechnology, Faculty of Science, KU Leuven, 3000 Leuven, Belgium.
Antony V SamrotSchool of Bioscience, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jenjarom 42610, Malaysia.
Vijayakumar GosuDepartment of Animal Biotechnology, Jeonbuk National University, Jeonju 54896, Republic of Korea.
Nanthini SadasivamDepartment of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.
In-Kyu ParkDepartment of Biomedical Sciences and BioMedical Sciences Graduate Program (BMSGP), Chonnam National University Medical School, Gwangju 61469, Republic of Korea.ORCID 0000-0003-1616-9153
Kamalakannan RadhakrishnanSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0002-0890-8692
Don-Kyu KimDepartment of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0002-6251-6438

Funding

National Research Foundation of Korea 2021R1A2C1011136
6 · The paper itself

Abstract

Reactive oxygen species (ROS) play a significant role in the survival and decline of various biological systems. In liver-related metabolic disorders such as steatohepatitis, ROS can act as both a cause and a consequence. Alcoholic steatohepatitis (ASH) and non-alcoholic steatohepatitis (NASH) are two distinct types of steatohepatitis. Recently, there has been growing interest in using medications that target ROS formation and reduce ROS levels as a therapeutic approach for oxidative stress-related liver disorders. Mammalian systems have developed various antioxidant defenses to protect against excessive ROS generation. These defenses modulate ROS through a series of reactions, limiting their potential impact. However, as the condition worsens, exogenous antioxidants become necessary to control ROS levels. Nanotechnology has emerged as a promising avenue, utilizing nanocomplex systems as efficient nano-antioxidants. These systems demonstrate enhanced delivery of antioxidants to the target site, minimizing leakage and improving targeting accuracy. Therefore, it is essential to explore the evolving field of nanotechnology as an effective means to lower ROS levels and establish efficient therapeutic interventions for oxidative stress-related liver disorders.

Indexed as

antioxidantsliver diseasenanoparticlesoxidative stressROS

Identifiers

PMID37507944
PMCPMC10376173

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.