Evidence map›Paper›PMID 37507883›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Regulation of Redox Profile and Genomic Instability by Physical Exercise Contributes to Neuroprotection in Mice with Experimental Glioblastoma.

Luis F B Marqueze, Amanda K Costa, Giulia S Pedroso, Franciane F Vasconcellos, Bruna I Pilger, Schellen Kindermann, Vanessa M Andrade, Ana C B Alves, Tatyana Nery, Aderbal A Silva and 6 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Luis F B MarquezeGraduate Program in Health Sciences, School of Life Sciences and Medicine, Pontifical Catholic University of Paraná, Curitiba 80215-200, Brazil.ORCID 0000-0002-4738-1440
Amanda K CostaGraduate Program in Health Sciences, School of Life Sciences and Medicine, Pontifical Catholic University of Paraná, Curitiba 80215-200, Brazil.
Giulia S PedrosoGraduate Program in Health Sciences, School of Life Sciences and Medicine, Pontifical Catholic University of Paraná, Curitiba 80215-200, Brazil.
Franciane F VasconcellosGraduate Program in Health Sciences, School of Life Sciences and Medicine, Pontifical Catholic University of Paraná, Curitiba 80215-200, Brazil.
Bruna I PilgerGraduate Program in Health Sciences, School of Life Sciences and Medicine, Pontifical Catholic University of Paraná, Curitiba 80215-200, Brazil.
Schellen KindermannGraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma 88806-000, Brazil.
Vanessa M AndradeGraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma 88806-000, Brazil.
Ana C B AlvesDepartment of Physical Therapy, Federal University of Santa Catarina, Araranguá 88905-120, Brazil.
Tatyana NeryDepartment of Physical Therapy, Federal University of Santa Catarina, Araranguá 88905-120, Brazil.
Aderbal A SilvaDepartment of Physical Therapy, Federal University of Santa Catarina, Araranguá 88905-120, Brazil.ORCID 0000-0002-6825-3333
Stephanie R S CarvalhalDepartment of Physiology, Federal University of Parana, Curitiba 81531-970, Brazil.
Matheus F ZazulaDepartment of Physiology, Federal University of Parana, Curitiba 81531-970, Brazil.ORCID 0000-0002-4760-5977
Katya NaliwaikoDepartment of Physiology, Federal University of Parana, Curitiba 81531-970, Brazil.
Luiz C FernandesDepartment of Physiology, Federal University of Parana, Curitiba 81531-970, Brazil.
Zsolt RadakResearch Institute of Sport Science, University of Physical Education, Alkotas u. 44, H-1123 Budapest, Hungary.ORCID 0000-0003-1297-6804
Ricardo A PinhoGraduate Program in Health Sciences, School of Life Sciences and Medicine, Pontifical Catholic University of Paraná, Curitiba 80215-200, Brazil.ORCID 0000-0003-3116-4553
Pontifícia Universidade Católica do Paraná · BRUniversidade Federal do Paraná · BRUniversidade Federal de Santa Catarina · BRUniversidade do Extremo Sul Catarinense · BRHungarian University of Sports Science · HU

Funding

National Council for Scientific and Technological Development 307669/2019-0
6 · The paper itself

Abstract

Glioblastoma (GBM) is an aggressive, common brain cancer known to disrupt redox biology, affecting behavior and DNA integrity. Past research remains inconclusive. To further understand this, an investigation was conducted on physical training's effects on behavior, redox balance, and genomic stability in GBMA models. Forty-seven male C57BL/6J mice, 60 days old, were divided into GBM and sham groups (

Indexed as

brain tumorgenomic stabilityglioblastomaoxidative stressphysical exercise

Identifiers

PMID37507883
PMCPMC10376052
OpenAlexW4382064209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.