Evidence map›Paper›PMID 37507874›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Antioxidants Improve the Proliferation and Efficacy of hUC-MSCs against H

Zhaojuan Zheng, Xia Wang, Liming Ouyang, Wenxia Chen, Lixin Zhang, Yulin Cao

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  8. Crosstalk between MSC-extracellular vesicles andFrontiers in pharmacology · 2025
    Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhaojuan ZhengState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0009-0005-5782-7601
Xia WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Liming OuyangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0000-0003-3507-7895
Wenxia ChenState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Lixin ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Yulin CaoBeijing Tang Yi Hui Kang Biomedical Technology Co., Ltd., Beijing 100032, China.
East China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human umbilical cord mesenchymal stem cells (hUC-MSCs) are broadly applied in clinical treatment due to convenient accessibility, low immunogenicity, and the absence of any ethical issues involved. However, the microenvironment of inflammatory tissues may cause oxidative stress and induce senescence in transplanted hUC-MSCs, which will further reduce the proliferation, migration ability, and the final therapeutic effects of hUC-MSCs. Beta-nicotinamide mononucleotide (NMN) and coenzyme Q10 (CoQ10) are famous antioxidants and longevity medicines that could reduce intracellular reactive oxygen species levels by different mechanisms. In this study, hUC-MSCs were treated in vitro with NMN and CoQ10 to determine if they could reduce oxidative stress caused by hydrogen peroxide (H

Indexed as

cell proliferationcoenzyme Q10human umbilical cord mesenchymal stem cells (hUC-MSCs)nicotinamide mononucleotide (NMN)RNAseqsenescence

Identifiers

PMID37507874
PMCPMC10376626
OpenAlexW4382138054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.