Hydrogen Cyanamide Causes Reversible G2/M Cell Cycle Arrest Accompanied by Oxidation of the Nucleus and Cytosol.

Yazhini Velappan, Ambra de Simone, Santiago Signorelli, John A Considine, Christine H Foyer, Michael J Considine

Open access · goldAbstract read

In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 42% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Yazhini VelappanThe UWA Institute of Agriculture, The University of Western Australia, Perth, WA 6009, Australia.

Ambra de SimoneCentre for Plant Sciences, Faculty of Biology, University of Leeds, Leeds LS2 9JT, UK.

Santiago SignorelliFood and Plant Biology Group, Departamento de Biología Vegetal, Facultad de Agronomía, Universidad de la República, Sayago CP 12900, Uruguay.ORCID 0000-0002-1854-3164

John A ConsidineThe UWA Institute of Agriculture, The University of Western Australia, Perth, WA 6009, Australia.

Christine H FoyerSchool of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston B15 2TT, UK.ORCID 0000-0001-5989-6989

Michael J ConsidineThe UWA Institute of Agriculture, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-4468-6820

The University of Western Australia · AUUniversidad de la República de Uruguay · UYUniversity of Birmingham · GBUniversity of Leeds · GB

Funding

Australian Research Council DP150103211Australian Research Council FT180100409European Union FP7: KBBE-2012-6-311840Wine Australia GWR Ph1201

6 · The paper itself

Abstract

Hydrogen cyanamide (HC) has been widely used in horticulture to trigger bud burst following dormancy. Its use has been banned in some countries due to human health concerns, however the search for effective safe alternatives is delayed by lack of knowledge of the mechanism of HC action. Earlier studies demonstrate that HC stimulates the production of reactive oxygen species (ROS) and alters the rate of cell division. However, the relationships between HC effects on ROS, redox (reduction/oxidation) homeostasis and cell division are unknown. This study used

Indexed as

cell cyclehydrogen cyanamidemeristemquiescenceredoxroGFP2

Identifiers

PMID37507870

DOI10.3390/antiox12071330

PMCPMC10376265

OpenAlexW4382064751

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.