Evidence map›Paper›PMID 37507791›Full record

ArticleJournal of experimental & clinical cancer research : CR2023

The new world of RNA diagnostics and therapeutics.

Giovanni Blandino, Roberto Dinami, Marco Marcia, Eleni Anastasiadou, Brid M Ryan, Alina Catalina Palcau, Luigi Fattore, Giulia Regazzo, Rosanna Sestito, Rossella Loria and 9 more

Abstract read
In one paragraph

Article in Journal of experimental & clinical cancer research : CR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. MicroRNA in cancer therapy: breakthroughs and challenges in early clinical applications.Journal of experimental & clinical cancer research : CR · 2025
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Giovanni BlandinoTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy. giovanni.blandino@ifo.it.
Roberto DinamiTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Marco MarciaEMBL, Grenoble, France.
Eleni AnastasiadouDepartment of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.
Brid M RyanMiRNA Therapeutics, London, UK.
Alina Catalina PalcauTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Luigi FattoreSAFU Laboratory, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Giulia RegazzoTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Rosanna SestitoPreclinical models and new therapeutic agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Rossella LoriaUnit of Cellular Networks and Molecular Therapeutic Targets, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Ana Belén Díaz MéndezTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Maria Chiara CappellettoTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Claudio PulitoTranslational Oncology Research Unit, IRCCS, Regina Elena National Cancer Institute, Rome, Italy.
Laura MonteonofrioUnit of Cellular Networks and Molecular Therapeutic Targets, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
George A CalinMDAnderson, University of Texas, Houston, USA.
Gabriella SozziIRCCS, National Cancer Institute, Milan, Italy.
Jit Kong CheongNational University of Singapore Yong Loo Lin School of Medicine, NUS Centre for Cancer Research and Mirxes Lab Pte Ltd, Singapore, Singapore.
Ranit AharonovPangaea Biomed, Tel Aviv, Israel.
Gennaro CilibertoScientific Direction, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 5th Workshop IRE on Translational Oncology was held in Rome (Italy) on 27-28 March at the IRCCS Regina Elena National Cancer Institute. This meeting entitled "The New World of RNA diagnostics and therapeutics" highlightes the significant progress in the RNA field made over the last years. Research moved from pure discovery towards the development of diagnostic biomarkers or RNA-base targeted therapies seeking validation in several clinical trials. Non-coding RNAs in particular have been the focus of this workshop due to their unique properties that make them attractive tools for the diagnosis and therapy of cancer.This report collected the presentations of many scientists from different institutions that discussed recent oncology research providing an excellent overview and representative examples for each possible application of RNA as biomarker, for therapy or to increase the number of patients that can benefit from precision oncology treatment.In particular, the meeting specifically emphasized two key features of RNA applications: RNA diagnostic (Blandino, Palcau, Sestito, Díaz Méndez, Cappelletto, Pulito, Monteonofrio, Calin, Sozzi, Cheong) and RNA therapeutics (Dinami, Marcia, Anastasiadou, Ryan, Fattore, Regazzo, Loria, Aharonov).

Indexed as

NeoplasmsBiomarkersHumansItalyMedical OncologyPrecision MedicineBiomarkersCell cycle regulationEpigeneticsRNA evolutionRNA structureSplicing

Identifiers

PMID37507791
PMCPMC10386627

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.