Evidence map›Paper›PMID 37507787›Full record

ArticleBMC oral health2023

Presence of Candida and its associated factors in participants attending oral cancer screening in the lower northeastern area of Thailand.

Krongkan Deeiam, Jintana Pankam, Vanvisa Sresumatchai, Patama Visedketkan, Warut Jindavech, Dulyapong Rungraungrayabkul, Kununya Pimolbutr, Boworn Klongnoi, Siribang-On Piboonniyom Khovidhunkit

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Journal of oral microbiology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Krongkan DeeiamDepartment of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, 6 Yothi Rd. Ratchathewi, Bangkok, 10400, Thailand.
Jintana PankamDevelopment of Disease Management Model for Oral Cancer with an Integration Network of Screening, Surveillance, and Treatment from Primary Care Unit to Tertiary Care in Nakhonratchasima Province Project, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Vanvisa SresumatchaiDepartment of Family Health, Faculty of Public Health, Mahidol University, Bangkok, Thailand.
Patama VisedketkanDental Department, Khamthaleso Hospital, Nakorn Ratchasima, Thailand.
Warut JindavechDental Department, Prathai Hospital, Nakorn Ratchasima, Thailand.
Dulyapong RungraungrayabkulDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Kununya PimolbutrDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Boworn KlongnoiDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Siribang-On Piboonniyom KhovidhunkitDepartment of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, 6 Yothi Rd. Ratchathewi, Bangkok, 10400, Thailand. siribangon.pib@mahidol.edu.
Mahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCertain evidence indicated high prevalence of Candida in oral potentially malignant disorders (OPMDs) and oral cancer (OC). This study was aimed to investigate the presence of Candida and its associated factors in participants who attended the oral cancer screening program in the lower northeastern districts of Thailand.

methodsConvenient participants residing in the lower northeastern districts of Thailand who attended the oral cancer screening were enrolled. A questionnaire retrieving demographic characteristics, risk factors of oral cancer, and risk of having Candida was completed. Oral examination was performed by oral medicine specialists or oral surgeons. The participants were categorized into 4 groups according to their clinical diagnosis, namely normal oral mucosa (NOM), OPMDs/OC, non-OPMDs/OC and clinically suspected oral candidiasis (CSOC). Stimulated saliva flow rate was measured. Dip-slide test was performed in each participant to evaluate the presence of Candida. The levels of Candida were categorized into high and low levels according to the score received from the dip-slide test. Factors associated with high levels of Candida were identified using multivariate logistic regression analysis.

resultsA total of 577 participants were recruited. High levels of Candida were found in 31.3%, 24.7%, 25.9% and 18.1% in the OPMDs/OC, the non-OPMDs/OC, the CSOC and the NOM groups, respectively. According to multivariate logistic regression analysis, age above 60 years, female gender, betel quid chewing habit, use of denture, hyposalivation, and being in the CSOC group were found to be significantly associated with high levels of Candida.

conclusionHigher number of participants in the OPMDs/OC group was found to have high levels of Candida. Increasing age, female gender, betel quid chewing habit, use of denture, hyposalivation and having CSOC lesions were associated with high levels of Candida.

Indexed as

Mouth DiseasesMouth NeoplasmsPrecancerous ConditionsXerostomiaArecaCandidaEarly Detection of CancerFemaleHumansMiddle AgedThailandCancerCandidaDip-slide testOral cancerOral cancer screening programOral potentially malignant disorders

Identifiers

PMID37507787
PMCPMC10386231
OpenAlexW4385342902

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.