ArticleThe journal of headache and pain2023
MRI features of idiopathic intracranial hypertension are not prognostic of visual and headache outcome.
Article in The journal of headache and pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Therapeutic role of GLP-1 receptor agonists in idiopathic intracranial hypertension: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- MRI features in atypical idiopathic intracranial hypertension.European radiology · 2026Article
- Hallmarks of headache disorders: part 5 - secondary headaches.The journal of headache and pain · 2026Review
- Patterns of Retinal Damage and Visual Long-Term Consequences in Patients With Idiopathic Intracranial Hypertension.Neurology · 2025Article
- How can MRI descriptors be optimally combined to predict idiopathic intracranial hypertension?The British journal of radiology · 2025Article
- Current Understanding of the Pathophysiology of Idiopathic Intracranial Hypertension.Current neurology and neuroscience reports · 2025Review
- Longitudinal visual outcomes in idiopathic intracranial hypertension: the role of early prognostic indicators and risk stratification in disease management.Journal of neurology · 2025Article
- Visual prognosis in idiopathic intracranial hypertension: observations from a retrospective cohort in Germany.Frontiers in neurology · 2025Article
- Idiopathic intracranial hypertension: Imaging and clinical fundamentals.World journal of radiology · 2024Review
- Disability and Patient-Reported Satisfaction in Women with Idiopathic Intracranial Hypertension: A Comparative Study of Venous Sinus Stenting and Medical Management.Diagnostics (Basel, Switzerland) · 2024Article
- Idiopathic intracranial hypertension in Asians: a retrospective dual-center study.The journal of headache and pain · 2024Article
- Transorbital B-mode ultrasound for the assessment of posterior globe flattening in idiopathic intracranial hypertension: a pilot study.The ultrasound journal · 2024Article
- Idiopathic intracranial hypertension in two twin sisters.BMJ case reports · 2024Article
- Clinical Course and Ophthalmologic Findings in Idiopathic Intracranial Hypertension and Pregnancy.Brain sciences · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIn idiopathic intracranial hypertension (IIH), certain MRI features are promising diagnostic markers, but whether these have prognostic value is currently unknown.
methodsWe included patients from the Vienna-Idiopathic-Intracranial-Hypertension (VIIH) database with IIH according to Friedman criteria and cranial MRI performed at diagnosis. Presence of empty sella (ES), perioptic subarachnoid space distension (POSD) with or without optic nerve tortuosity (ONT), posterior globe flattening (PGF) and transverse sinus stenosis (TSS) was assessed and multivariable regression models regarding visual outcome (persistent visual impairment/visual worsening) and headache outcome (headache improvement/freedom of headache) were fitted.
resultsWe included 84 IIH patients (88.1% female, mean age 33.5 years, median body mass index 33.7). At baseline, visual impairment was present in 70.2% and headache in 84.5% (54.8% chronic). Persistent visual impairment occurred in 58.3%, visual worsening in 13.1%, headache improvement was achieved in 83.8%, freedom of headache in 26.2%. At least one MRI feature was found in 78.6% and 60.0% had ≥3 features with POSD most frequent (64.3%) followed by TSS (60.0%), ONT (46.4%), ES (44.0%) and PGF (23.8%). In multivariable models, there was no association of any single MRI feature or their number with visual impairment, visual worsening, headache improvement or freedom. Visual impairment at baseline predicted persistent visual impairment (odds ratio 6.3, p<0.001), but not visual worsening. Chronic headache at baseline was significantly associated with lower likelihood of headache freedom (odds ratio 0.48, p=0.013), but not with headache improvement.
conclusionsMRI features of IIH are neither prognostic of visual nor headache outcome.
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