Evidence map›Paper›PMID 37507537›Full record

ArticleScientific reports2023

The effects of daptomycin on cell wall biosynthesis in Enterococcal faecalis.

Binayak Rimal, James Chang, Chengyin Liu, Raiyan Rashid, Manmilan Singh, Sung Joon Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Bacterial cell envelope-targeting antibiotics.Nature reviews. Microbiology · 2026
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Binayak RimalInstitute of Biomedical Studies, Baylor University, Waco, TX, 76798, USA.
James ChangDepartment of Chemistry One Bear Place #97046, Baylor University, Waco, TX, 76798, USA.
Chengyin LiuDepartment of Chemistry, Howard University, Washington, DC, 20059, USA.
Raiyan RashidDepartment of Chemistry, Howard University, Washington, DC, 20059, USA.
Manmilan SinghDepartment of Chemistry, Washington University, St. Louis, MO, 63110, USA.
Sung Joon KimDepartment of Chemistry, Howard University, Washington, DC, 20059, USA. sung.kim@howard.edu.
Howard University · USBaylor University · USJohns Hopkins Medicine · USWashington University in St. Louis · US

Funding

The Role of the Foxo Pathway in the Control of Culex pipiens DiapauseR15AI139861 · NIAID · BAYLOR UNIVERSITY · PI Cheolho Sim · 2018 to 2026
$1.3M
GLYCOPEPTIDE COMPLEXES WITH BACTERIAL CELL WALLS BY REDORR01GM116130 · NIGMS · WASHINGTON UNIVERSITY · PI PATTI, GARY J · 2015 to 2018
$1.2M
NIAID NIH HHS R15 AI139861NIGMS NIH HHS R01 GM116130
6 · The paper itself

Abstract

Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious infections by multidrug-resistant Gram-positive pathogens. Its mode of action is considered to be multifaceted, encompassing the targeting and depolarization of bacterial cell membranes, alongside the inhibition of cell wall biosynthesis. To characterize the daptomycin mode of action,

Indexed as

DaptomycinAnti-Bacterial AgentsCell WallEnterococcus faecalisPeptidoglycanAnti-Bacterial AgentsDaptomycinPeptidoglycan

Identifiers

PMID37507537
PMCPMC10382475
OpenAlexW4385343651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.