Evidence map›Paper›PMID 37507410›Full record

ArticleNPJ Regenerative medicine2023

LRRC10 regulates mammalian cardiomyocyte cell cycle during heart regeneration.

Rebecca J Salamon, Megan C McKeon, Jiyoung Bae, Xiaoya Zhang, Wyatt G Paltzer, Kayla N Wanless, Alyssa R Schuett, Dakota J Nuttall, Stephen A Nemr, Rupa Sridharan and 3 more

Open access · goldAbstract read
In one paragraph

Article in NPJ Regenerative medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rebecca J SalamonDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.ORCID http://orcid.org/0000-0001-7934-1868
Megan C McKeonDepartment of Biomolecular Chemistry, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Jiyoung BaeDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.ORCID http://orcid.org/0000-0003-2367-7578
Xiaoya ZhangDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.ORCID http://orcid.org/0000-0002-1614-0011
Wyatt G PaltzerDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Kayla N WanlessDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Alyssa R SchuettDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Dakota J NuttallDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.ORCID http://orcid.org/0000-0002-2472-528X
Stephen A NemrDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Rupa SridharanDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Youngsook LeeDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.
Timothy J KampDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA.ORCID http://orcid.org/0000-0003-2103-7876
Ahmed I MahmoudDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, 53705, USA. aimahmoud@wisc.edu.ORCID http://orcid.org/0000-0003-1528-7393
University of Wisconsin–Madison · USOklahoma State University · US

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseU01HL134764 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BURSAC, NENAD, KAMP, TIMOTHY J. · 2016 to 2022
$7.7M
R01 Renewal: Collaboration of chromatin remodeling and signaling pathways in pluripotencyR01GM113033 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SRIDHARAN, RUPA · 2015 to 2023
$2.9M
Metabolic Reprogramming of the Adult Heart to a Regenerative StateR01HL166256 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Ahmed I Mahmoud · 2023 to 2026
$1.8M
Targeting Metabolism To Stimulate Adult Heart RegenerationR56HL155617 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAHMOUD, AHMED I · 2021 to 2021
$393k
NHLBI NIH HHS R01 HL166256NHLBI NIH HHS R56 HL155617NHLBI NIH HHS T32 HL007936NHLBI NIH HHS U01 HL134764NIGMS NIH HHS R01 GM113033NIGMS NIH HHS T32 GM007133
6 · The paper itself

Abstract

Leucine-rich repeat containing 10 (LRRC10) is a cardiomyocyte-specific protein, but its role in cardiac biology is little understood. Recently Lrrc10 was identified as required for endogenous cardiac regeneration in zebrafish; however, whether LRRC10 plays a role in mammalian heart regeneration remains unclear. In this study, we demonstrate that Lrrc10

Identifiers

PMID37507410
PMCPMC10382521
OpenAlexW4385347769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.