Evidence map›Paper›PMID 37507351›Full record

ArticleThe International journal of eating disorders2024

Course and outcome in individuals with atypical anorexia nervosa: Findings from the Study of Refeeding to Optimize iNpatient Gains (StRONG).

Neville H Golden, Cynthia J Kapphahn, Jing Cheng, Anna Kreiter, Amanda E Downey, Erin C Accurso, Vanessa I Machen, Sally H Adams, Sara M Buckelew, Anna-Barbara Moscicki and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal of eating disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Weight Stigma in Medicine.Focus (American Psychiatric Publishing) · 2025
    Article
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  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Neville H GoldenDepartment of Pediatrics, Division of Adolescent Medicine, Stanford University, Stanford, California, USA.ORCID 0000-0003-2262-6955
Cynthia J KapphahnDepartment of Pediatrics, Division of Adolescent Medicine, Stanford University, Stanford, California, USA.ORCID 0000-0002-5667-4157
Jing ChengDepartment of Preventive & Restorative Dental Sciences, University of California, San Francisco, California, USA.
Anna KreiterDepartment of Pediatrics, Division of Adolescent Medicine, Stanford University, Stanford, California, USA.
Amanda E DowneyDepartment of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, San Francisco, California, USA.ORCID 0000-0002-5206-7798
Erin C AccursoDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID 0000-0002-5521-6381
Vanessa I MachenDepartment of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, San Francisco, California, USA.
Sally H AdamsDepartment of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, San Francisco, California, USA.
Sara M BuckelewDepartment of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, San Francisco, California, USA.
Anna-Barbara MoscickiDepartment of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, Los Angeles, California, USA.
Daniel Le GrangeDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID 0000-0001-7293-9496
Andrea K GarberDepartment of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, San Francisco, California, USA.
University of California, San Francisco · USStanford University · USUniversity of California, Los Angeles · US

Funding

UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jeremy F Reiter · 2015 to 2026
$14.6M
Multi-center Randomized Controlled Trial of Refeeding in Anorexia NervosaR01HD082166 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARBER, ANDREA K · 2015 to 2025
$5.7M
Adapting and Implementing Family-Based Treatment for Youth with Anorexia Nervosa in Publicly-Funded SettingsK23MH120347 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ACCURSO, ERIN CECILIA · 2019 to 2023
$846k
NICHD NIH HHS R01 HD082166NIDDK NIH HHS P30 DK098722NIH HHS RO1HD082166NIMH NIH HHS K23 MH120347
6 · The paper itself

Abstract

objectiveWe previously reported that participants with atypical anorexia nervosa (atypical AN) had higher historical and admission weights, greater eating disorder psychopathology, but similar rates of amenorrhea and weight suppression at baseline as compared to anorexia nervosa (AN); here, we compare 1-year outcomes.

methodWeight, % median body mass index (%mBMI), Eating Disorder Examination Questionnaire (EDE-Q) scores, resumption of menses, and rehospitalizations were examined at 3, 6, and 12 months post-discharge. Analyses (N = 111) compared changes in %mBMI, weight suppression, and EDE-Q scores over time between atypical AN and AN.

resultsAmong the participants (48 atypical AN, 63 AN), both groups gained weight but those with atypical AN had lower gains than those with AN in %mBMI (p = .02) and greater weight suppression (p = .002) over time. EDE-Q scores improved over time, independent of weight suppression, with no significant difference between atypical AN and AN. Groups did not differ by rates of resumption of menses (80% atypical AN, 76.9% AN) or rehospitalization (29.2% atypical AN, 37.9% AN). Greater weight suppression predicted longer time to restore menses and more days of rehospitalization. DISCUSSION: Individuals with atypical AN regained a smaller proportion of body mass and were more weight suppressed over time. Change in eating disorder cognitions, resumption of menses, and rehospitalization rates at 1-year follow-up did not differ between groups. There was no significant difference in weight suppression between groups for those who were psychologically improved at 12 months. Findings highlight limitations in our understanding of weight recovery in atypical AN. New metrics for recovery are urgently needed. PUBLIC SIGNIFICANCE: Little is known about outcome in atypical anorexia nervosa (atypical AN). We examined recovery metrics in young people with atypical AN and anorexia nervosa (AN) 1 year after medical hospitalization. Individuals with atypical AN showed slower weight gain and remained further from their pre-illness weight. There were no differences in the rates of psychological recovery, resumption of menses, or rehospitalization. New metrics are needed to assess recovery in atypical AN.

Indexed as

Anorexia NervosaAdolescentAftercareBody Mass IndexFemaleHumansInpatientsPatient DischargeWeight Gainanorexia nervosaatypical anorexia nervosacourseoutcome

Identifiers

PMID37507351
PMCPMC10822019
OpenAlexW4385332009

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.