Evidence map›Paper›PMID 37507330›Full record

ReviewSeminars in cell & developmental biology2024

Molecular cell types as functional units of the efferent vagus nerve.

Tatiana C Coverdell, Stephen B G Abbott, John N Campbell

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Vagal GABAergic signaling in autonomic control of cardiometabolic function.American journal of physiology. Cell physiology · 2026
    Review
  3. Review
  4. Review
  5. Cardiac vagal motor neurons.Current opinion in neurobiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tatiana C CoverdellBiomedical Sciences Graduate Program, University of Virginia, Charlottesville, VA 22903, USA.
Stephen B G AbbottDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22903, USA.
John N CampbellDepartment of Biology, University of Virginia, Charlottesville, VA 22903, USA. Electronic address: jnc4e@virginia.edu.
University of Virginia · US

Funding

TRAINING IN THE PHARMACOLOGICAL SCIENCEST32GM007055 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LYNCH, KEVIN R. · 1985 to 2022
$7.2M
Molecular and Functional Taxonomy of Cardiovagal NeuronsR01HL153916 · NHLBI · UNIVERSITY OF VIRGINIA · PI CAMPBELL, JOHN NELSON · 2021 to 2025
$3.1M
Role of presympathetic neurons of the hindbrain in cardiovascular controlR01HL148004 · NHLBI · UNIVERSITY OF VIRGINIA · PI ABBOTT, STEPHEN · 2019 to 2023
$2.6M
Identification of cell-type specific visual circuits in the ventral lateral geniculate nucleusR21EY033528 · NEI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CAMPBELL, JOHN N, FOX, MICHAEL A · 2022 to 2023
$441k
Genetic Dissection of Nucleus Ambiguus Neurons Controlling Cardiorespiratory FunctionsF31HL158187 · NHLBI · UNIVERSITY OF VIRGINIA · PI COVERDELL, TATIANA CLARISSA · 2021 to 2022
$46k
NEI NIH HHS R21 EY033528NHLBI NIH HHS F31 HL158187NHLBI NIH HHS R01 HL148004NHLBI NIH HHS R01 HL153916NIGMS NIH HHS T32 GM007055
6 · The paper itself

Abstract

The vagus nerve vitally connects the brain and body to coordinate digestive, cardiorespiratory, and immune functions. Its efferent neurons, which project their axons from the brainstem to the viscera, are thought to comprise "functional units" - neuron populations dedicated to the control of specific vagal reflexes or organ functions. Previous research indicates that these functional units differ from one another anatomically, neurochemically, and physiologically but have yet to define their identity in an experimentally tractable way. However, recent work with genetic technology and single-cell genomics suggests that genetically distinct subtypes of neurons may be the functional units of the efferent vagus. Here we review how these approaches are revealing the organizational principles of the efferent vagus in unprecedented detail.

Indexed as

Neurons, EfferentVagus NerveNeuronsDorsal motor nucleus of the vagusNucleus ambiguusParasympathetic preganglionicTenth cranial nerveVagal motor neuron

Identifiers

PMID37507330
PMCPMC10811285
OpenAlexW4385364204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.