Evidence map›Paper›PMID 37507127›Full record

ArticleBMJ case reports2023

Recurrent group B stretococcus infection in an extremely premature infant: as a preterm neonate, infant and toddler.

Ina Schim van der Loeff, Christo Tsilifis, Khalid Abdelhafiz, Eleri J Williams

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ina Schim van der LoeffPaediatric Immunology and Infectious Diseases, Great North Children's Hospital, Newcastle upon Tyne, UK ina.schim@nhs.net.
Christo TsilifisPaediatric Immunology and Infectious Diseases, Great North Children's Hospital, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0002-1368-104X
Khalid AbdelhafizNeonatalogy, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Eleri J WilliamsPaediatric Immunology and Infectious Diseases, Great North Children's Hospital, Newcastle upon Tyne, UK.
Great North Children's Hospital · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report five discrete episodes of group B streptococcus (GBS) bacteraemia in an extremely premature infant, extending into early childhood. The first four episodes occurred during infancy despite appropriate treatment. Breastmilk was positive for group B streptococcal 16S DNA by polymerase chain reaction. The fifth episode occurred at 17 months of age, shortly after stopping antimicrobial prophylaxis.Radiological investigations did not identify a focus for recurrence of GBS bacteraemia, and immunological investigations and targeted whole genome sequencing yielded only transient hypogammaglobulinaemia of infancy, which resolved.This case highlights invasive GBS infection as a cause of infant morbidity. Premature infants are at particular risk of invasive as well as recurrent disease. GBS is typically a sensitive organism and each episode of GBS in our patient was effectively treated with penicillin. The role of breastmilk in recurrent GBS is controversial; in this case infant and mother isolated identical GBS serotypes and were concurrently treated with rifampicin.

Indexed as

BacteremiaPregnancy Complications, InfectiousStreptococcal InfectionsChild, PreschoolFemaleHumansInfantInfant, Extremely PrematureInfant, NewbornMilk, HumanPenicillinsPregnancyStreptococcus agalactiaePenicillinsInfectious diseasesNeonatal and paediatric intensive careNeurology (drugs and medicines)

Identifiers

PMID37507127
PMCPMC10387633
OpenAlexW4385340477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.