ArticleThe Plant cell2023
Deciphering the regulatory network of the NAC transcription factor FvRIF, a key regulator of strawberry (Fragaria vesca) fruit ripening.
Article in The Plant cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 78 citations in OpenAlex.
- FaNAC29: a novel gene positively regulating strawberry powdery mildew resistance.The New phytologist · 2026Article
- The PavPIF3/PavMYC2-PavMYB75L/PavCOP1 regulatory module integrates light and jasmonic acid signaling to regulate fruit coloration in blush sweet cherry.The Plant journal : for cell and molecular biology · 2026Article
- Dissecting gene regulatory networks driving grape berry ripening using comparative systems biology across nonclimacteric fleshy fruits: the NAC-centered hierarchy revisited.Horticulture research · 2026Review
- QTL mapping for berry firmness and functional characterization of a prioritized candidate gene VvNAC83 in grape.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Bifunctional transcription factors: recent advances in growth and development, stress resistance, and quality formation of fruits and vegetables.Horticulture research · 2026Article
- FcMAPK4-phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression.Journal of integrative plant biology · 2026Article
- Characterization and expression analysis of UBC gene family provide insights into the potential roles in pigment biosynthesis in pepper fruit.BMC genomics · 2026Article
- FaRIF as a key regulator of strawberry fruit ripening: deciphering its targets and interaction networks.Horticulture research · 2026Article
- Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50-JAZ5 Module.Plant biotechnology journal · 2026Article
- Genome-wide identification of CONSTANS-LIKE genes and functional analysis of FaCOL57 and FaCOL59 in regulating anthocyanin and sugar synthesis in cultivated strawberry.BMC genomics · 2026Article
- Article
- Protein post-translational modifications: key switches coordinating fruit ripening regulatory networks.Horticulture research · 2026Article
- Genome-Wide Identification of Binding Motifs and Drought-Responsive Target Genes by the Transcription Factor ZmNAC20 in Maize.Plants (Basel, Switzerland) · 2026Article
- Dual benefits ofHorticulture research · 2026Article
- MicroRNA164d suppresses the HvNAC92-HvHKT1;5 module to enhance salinity tolerance in barley.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Strawberry cryptochrome FvCRY1 and FvCRY2 transcriptionally regulate anthocyanin biosynthesis and sugar metabolism.Molecular horticulture · 2025Article
- OsNTL2 confers rice osmotic stress resilience through coordinated transcriptional regulation of the ASC-GSH redox cycle and cell wall biosynthesis.Stress biology · 2025Article
- The role of pectate lyases in development and stress tolerance in plants.Molecular biology reports · 2025Review
- MdMAPK6-mediated phosphorylation of MdWRKY9 regulates apple fruit ripening through interaction with MdERF5L.Horticulture research · 2025Article
- PbrNAC34a- PbrMYB3/65- PbrACO2 cascade plays a role in citrate difference between the pericarp and cortex tissues of pear (P. bretschneideri Rehd.) fruit.Molecular horticulture · 2025Article
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9 authors at 4 institutions in 2 countries.
Funding
Abstract
The NAC transcription factor ripening inducing factor (RIF) was previously reported to be necessary for the ripening of octoploid strawberry (Fragaria × ananassa) fruit, but the mechanistic basis of RIF-mediated transcriptional regulation and how RIF activity is modulated remains elusive. Here, we show that FvRIF in diploid strawberry, Fragaria vesca, is a key regulator in the control of fruit ripening and that knockout mutations of FvRIF result in a complete block of fruit ripening. DNA affinity purification sequencing coupled with transcriptome deep sequencing suggests that 2,080 genes are direct targets of FvRIF-mediated regulation, including those related to various aspects of fruit ripening. We provide evidence that FvRIF modulates anthocyanin biosynthesis and fruit softening by directly regulating the related core genes. Moreover, we demonstrate that FvRIF interacts with and serves as a substrate of MAP kinase 6 (FvMAPK6), which regulates the transcriptional activation function of FvRIF by phosphorylating FvRIF at Thr-310. Our findings uncover the FvRIF-mediated transcriptional regulatory network in controlling strawberry fruit ripening and highlight the physiological significance of phosphorylation modification on FvRIF activity in ripening.
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