Evidence map›Paper›PMID 37505726›Full record

ArticleToxins2023

From Foodborne Disease Outbreak (FBDO) to Investigation: The Plant Toxin Trap, Brittany, France, 2018.

Stéphanie Watier-Grillot, Sébastien Larréché, Christelle Mazuet, Frédéric Baudouin, Cécile Feraudet-Tarisse, Lise Holterbach, Aïssata Dia, Christelle Tong, Laure Bourget, Sophie Hery and 8 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Calcium propionate in tortillas - a likely cause of a large outbreak of acute gastrointestinal illness, Finland, 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Stéphanie Watier-GrillotFrench Armed Forces Centre for Epidemiology and Public Health (CESPA), 13014 Marseille, France.
Sébastien LarréchéBégin Military Teaching Hospital, 94160 Saint-Mandé, France.
Christelle MazuetNational Reference Centre for Anaerobic Bacteria and Botulism, Institut Pasteur, Paris Cité University, CEDEX 15, 75724 Paris, France.
Frédéric BaudouinIMPROVE Laboratory, 80480 Dury, France.
Cécile Feraudet-TarisseDepartment of Medications and Healthcare Technologies (DMTS), Paris-Saclay University, CEA, INRAE, SPI, 91190 Gif-sur-Yvette, France.ORCID 0000-0002-9098-1767
Lise HolterbachFrench Armed Forces Centre for Epidemiology and Public Health (CESPA), 13014 Marseille, France.
Aïssata DiaFrench Armed Forces Centre for Epidemiology and Public Health (CESPA), 13014 Marseille, France.
Christelle TongFrench Armed Forces Centre for Epidemiology and Public Health (CESPA), 13014 Marseille, France.
Laure BourgetLaboratory of the French Armed Forces Commissariat, 49130 Les Ponts-de-Cé, France.
Sophie HeryNaval Group, Department of Occupational Health, 29200 Brest, France.
Emmanuel PottierBrest Arsenal Medical Center, 29200 Brest, France.
Olivier BouillandBrest Arsenal Medical Center, 29200 Brest, France.
Marc TantiFrench Armed Forces Centre for Epidemiology and Public Health (CESPA), 13014 Marseille, France.
Audrey MerensBégin Military Teaching Hospital, 94160 Saint-Mandé, France.
Stéphanie SimonDepartment of Medications and Healthcare Technologies (DMTS), Paris-Saclay University, CEA, INRAE, SPI, 91190 Gif-sur-Yvette, France.ORCID 0000-0002-6071-8255
Laure DiancourtNational Reference Centre for Anaerobic Bacteria and Botulism, Institut Pasteur, Paris Cité University, CEDEX 15, 75724 Paris, France.
Aurélie ChesnayLaboratory of the French Armed Forces Commissariat, 49130 Les Ponts-de-Cé, France.
Vincent Pommier de SantiFrench Armed Forces Centre for Epidemiology and Public Health (CESPA), 13014 Marseille, France.
Centre de recherche en Epidémiologie et Santé des Populations · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInserm · FRInstitut Pasteur · FRService de Santé des Armées · FRAix-Marseille Université · FRNaval Group (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On 6 July 2018, the Center for Epidemiology and Public Health of the French Armed Forces was informed of an outbreak of acute gastroenteritis among customers of a dining facility at a military base in Brittany, France. A total of 200 patients were reported out of a population of 1700 (attack rate: 12%). The symptoms were mainly lower digestive tract disorders and occurred rapidly after lunch on 5 July (median incubation period: 3.3 h), suggesting a toxin-like pathogenic process. A case-control survey was carried out (92 cases and 113 controls). Statistical analysis pointed to the chili con carne served at lunch on 5 July as the very likely source of poisoning. Phytohaemagglutinin, a plant lectin, was found in the chili con carne at a concentration above the potentially toxic dose (400 HAU/gram). The raw kidney beans incorporated in the chili con carne presented a high haemagglutination activity (66,667 HAU/gram). They were undercooked, and the phytohaemagglutinin was not completely destroyed. FBDOs due to PHA are poorly documented. This study highlights the need to develop methods for routine testing of plant toxins in food matrices. Improved diagnostic capabilities would likely lead to better documentation, epidemiology, and prevention of food-borne illnesses caused by plant toxins.

Indexed as

Foodborne DiseasesGastroenteritisToxins, BiologicalDisease OutbreaksFranceHumansMeatToxins, BiologicalClostridium perfringensfoodborne outbreaklectinPhaseolus vulgarisphytohaemagglutininred kidney beantoxin

Identifiers

PMID37505726
PMCPMC10467087
OpenAlexW4384201940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.