Evidence map›Paper›PMID 37505637›Full record

ArticleTropical medicine and infectious disease2023

Managing Comorbidities, Determinants and Disability at Start and End of TB Treatment under Routine Program Conditions in China.

Yuhong Liu, Yan Lin, Yuxian Sun, Pruthu Thekkur, Changhao Cheng, Yuecui Li, Yunzhen Shi, Jun Jiang, Jiong Liao, Chuangui Nie and 13 more

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 7 countries.

Yuhong LiuBeijing Chest Hospital, Capital Medical University, No. 9 Beiguan Ave, Tongzhou, Beijing 101149, China.
Yan LinInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.ORCID 0000-0002-7055-3183
Yuxian SunBeijing Chest Hospital, Capital Medical University, No. 9 Beiguan Ave, Tongzhou, Beijing 101149, China.
Pruthu ThekkurInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.ORCID 0000-0001-5257-5074
Changhao ChengWuhan Pulmonary Hospital, No. 28 Baofengyilu, Qiaokou, Wuhan 430000, China.
Yuecui LiThe First People's Hospital of Yongkang, No. 599 Jinshan West Road, Yongkang 321300, China.
Yunzhen ShiDongyang People's Hospital, No. 60 Wuning West Road, Dongyang 322100, China.
Jun JiangThe Third People's Hospital of Yichang City, No. 32 Gangyaolu, Yichang 443000, China.
Jiong LiaoThe People's Hospital of Laiban, No. 159 Pangudadao, Laiban 546100, China.
Chuangui NieXiangyang Institute of Tuberculosis Control and Prevention, No. 20 Xinhuala, Xiangyang 441000, China.
Wenyan SunEzhou Third Hospital, No. 16 Minxin West Road, Ezhou 436000, China.
Chengyuan LiangBaise City People's Hospital, No. 8 Chengxianglu, Youjiang, Baise 533000, China.
Xiaojuan ZhangZhongwei People's Hospital, Gulouxijie, Zhongwei 755000, China.
Sang LiuGuangxi Chest Hospital, No. 8 Yangjiaoshanlu, Yufeng, Liuzhou 545000, China.
Yan MaThe People's Hospital of Tongxin, Xueyuanlu, Tongxi, Yuhaizhen 751100, China.
Selma Dar BergerInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.
Srinath SatyanarayanaInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.ORCID 0000-0002-5420-2551
Ajay M V KumarInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.ORCID 0000-0003-1011-8531
Mohammed KhogaliInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 17666, United Arab Emirates.
Rony ZachariahUNICEF, UNDP, World Bank, World Health Organization, Special Programme for Research and Training in Tropical Diseases (TDR), Avenue Appia 20, 1211 Geneva, Switzerland.ORCID 0000-0002-2915-9328
Jonathan E GolubJohns Hopkins Center for Tuberculosis, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Liang LiBeijing Chest Hospital, Capital Medical University, No. 9 Beiguan Ave, Tongzhou, Beijing 101149, China.
Anthony D HarriesInternational Union Against Tuberculosis and Lung Disease, 2 Rue Jean Lantier, 75001 Paris, France.ORCID 0000-0001-6113-9741
Capital Medical University · CNInternational Union Against Tuberculosis and Lung Disease · FRWorld Health Organization Regional Office for South-East Asia · INBaise University · CNEzhou Central Hospital · CNGuangxi Zhuang Autonomous Region Brain Hospital · CNJohns Hopkins University · USSecond Hospital of Yichang · CNUnited Arab Emirates University · AEUniversity of London · GBWenzhou Medical University · CNWorld Health Organization · CHWuhan Pulmonary Hospital · CNYenepoya University · INZhongshan People's Hospital · CN

Funding

World Health Organization 001
6 · The paper itself

Abstract

Many patients with tuberculosis (TB) have comorbidities, risk determinants and disability that co-exist at diagnosis, during and after TB treatment. We conducted an observational cohort study in 11 health facilities in China to assess under routine program conditions (i) the burden of these problems at the start and end of TB treatment and (ii) whether referral mechanisms for further care were functional. There were 603 patients registered with drug-susceptible TB who started TB treatment: 84% were symptomatic, 14% had diabetes, 14% had high blood pressure, 19% smoked cigarettes, 10% drank excess alcohol and in 45% the 6 min walking test (6MWT) was abnormal. Five patients were identified with mental health disorders. There were 586 (97%) patients who successfully completed TB treatment six months later. Of these, 18% were still symptomatic, 12% had diabetes (the remainder with diabetes failed to complete treatment), 5% had high blood pressure, 5% smoked cigarettes, 1% drank excess alcohol and 25% had an abnormal 6MWT. Referral mechanisms for the care of comorbidities and determinants worked well except for mental health and pulmonary rehabilitation for disability. There is need for more programmatic-related studies in other countries to build the evidence base for care of TB-related conditions and disability.

Indexed as

6 min walking testChinacigarette smokingdiabetes mellitusdisabilityexcess alcohol drinkinghigh blood pressuremental health disorderSORT ITtuberculosis

Identifiers

PMID37505637
PMCPMC10383887
OpenAlexW4382465555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.