ReviewToxics2023
Toxicity of Heavy Metals and Recent Advances in Their Removal: A Review.
Review in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
105 citing papers in PubMed, 1 synthesis or guideline pooled it, 427 citations in OpenAlex.
- Toxic Metal in Plant-Based Therapeutics: Contamination Pathways, Oxidative Stress Induction, and Onset of Disease.TheScientificWorldJournal · 2026Pooled it
- Ascorbic Acid as a Dual Therapeutic and Preventive Agent against Lead and Cadmium Toxicity: Evidence from Controlled Quail Experiments.Biological trace element research · 2026Article
- Platinum accumulation in chemotherapy: toxicity mechanisms, challenges, and mitigation strategies.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Review
- Screening native plants for the sustainable phytoremediation of heavy metals in industrial areas of Bangladesh.RSC advances · 2026Article
- Review
- Developmental Toxicity of Lead and Copper in Chick Embryos: Morphometric and Histological Assessment of In Ovo Exposure.Biological trace element research · 2026Article
- Applications of Machine Learning in the Research of Heavy Metal(loid)s-Related Risk: A Scoping Review of Methodology.Toxics · 2026Review
- Heavy metal toxicity as a driver of endoplasmic reticulum stress and dysfunction.The FEBS journal · 2026Review
- Nano-Selenium-Mediated Alleviation of Chromium Toxicity and Selenium Biofortification ofPlants (Basel, Switzerland) · 2026Article
- Assessment of trace metal contamination in mangrove sediments-a case study from Guadeloupe Island, Caribbean Sea.Environmental monitoring and assessment · 2026Article
- Impact Assessment and Sustainable Remediation of Heavy Metal and Radioactive Contamination in Aquatic Systems: A Review.Water environment research : a research publication of the Water Environment Federation · 2026Review
- Lead contamination fixation through COScientific reports · 2026Article
- Synthesis and Characterization of CoFeACS omega · 2026Article
- Beyond the germ: Rethinking implant-related infections as a host-microbiota-biomaterial ecosystem.Biofilm · 2026Review
- Turning waste into a resource: coal fly ash as a sustainable approach for heavy metal removal in contaminated waters.Water science and technology : a journal of the International Association on Water Pollution Research · 2026Article
- Antibacterial Mechanism of Dipicolinic Acid AgainstBiomolecules · 2026Article
- Bioremediation of Produced Water by a Polyextremophilic, Heavy-Metal-ResistantACS ES&T water · 2026Article
- Recent advances in functionalized nanocarbon adsorbents for toxic pollutant removal: challenges and future perspectives.Discover nano · 2026Review
- Emerging strategies for heavy metal removal in soils: plant-microbe interactions and omics perspectives.Archives of microbiology · 2026Review
- Deciphering microbial approaches for heavy metal removal: an overview on their mechanisms, innovations and future horizons.Archives of microbiology · 2026Review
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural and anthropogenic sources of metals in the ecosystem are perpetually increasing; consequently, heavy metal (HM) accumulation has become a major environmental concern. Human exposure to HMs has increased dramatically due to the industrial activities of the 20th century. Mercury, arsenic lead, chrome, and cadmium have been the most prevalent HMs that have caused human toxicity. Poisonings can be acute or chronic following exposure via water, air, or food. The bioaccumulation of these HMs results in a variety of toxic effects on various tissues and organs. Comparing the mechanisms of action reveals that these metals induce toxicity via similar pathways, including the production of reactive oxygen species, the inactivation of enzymes, and oxidative stress. The conventional techniques employed for the elimination of HMs are deemed inadequate when the HM concentration is less than 100 mg/L. In addition, these methods exhibit certain limitations, including the production of secondary pollutants, a high demand for energy and chemicals, and reduced cost-effectiveness. As a result, the employment of microbial bioremediation for the purpose of HM detoxification has emerged as a viable solution, given that microorganisms, including fungi and bacteria, exhibit superior biosorption and bio-accumulation capabilities. This review deals with HM uptake and toxicity mechanisms associated with HMs, and will increase our knowledge on their toxic effects on the body organs, leading to better management of metal poisoning. This review aims to enhance comprehension and offer sources for the judicious selection of microbial remediation technology for the detoxification of HMs. Microbial-based solutions that are sustainable could potentially offer crucial and cost-effective methods for reducing the toxicity of HMs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.