Evidence map›Paper›PMID 37505440›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2023

Arterial Stiffness in Overweight and Obesity: Association with Sex, Age, and Blood Pressure.

John G Eikås, Eva Gerdts, Hilde Halland, Helga Midtbø, Dana Cramariuc, Ester Kringeland

Open access · hybridAbstract read
In one paragraph

Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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  6. Pulse Wave Velocity Progression Determinants: No Significant Association with Novel Lipids Parameter.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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  8. Stronger Association Between Blood Pressure and Arterial Stiffness in Older Women than Men: The Hordaland Health Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  9. Sex Differences in Ambulatory Central Blood Pressure and Arterial Stiffness in Hemodialysis Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John G EikåsDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway. jei033@uib.no.ORCID http://orcid.org/0009-0001-5799-0864
Eva GerdtsDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway.ORCID http://orcid.org/0000-0003-4109-2311
Hilde HallandDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway.ORCID http://orcid.org/0000-0002-7882-6617
Helga MidtbøDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway.ORCID http://orcid.org/0000-0002-3558-9914
Dana CramariucDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway.ORCID http://orcid.org/0000-0002-1593-2017
Ester KringelandDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway.ORCID http://orcid.org/0000-0002-9015-741X
Haukeland University Hospital · NOUniversity of Bergen · NO

Funding

Helse Vest 911402
6 · The paper itself

Abstract

introductionObesity has been associated with increased arterial stiffness. Sex-differences in arterial stiffness in obesity have been less explored.

aimTo explore sex-differences in arterial stiffness by applanation tonometry in 323 women and 225 with overweight and obesity, free of cardiovascular disease.

methodsCovariables of arterial stiffness were identified in multivariable linear regression analyses in the total cohort and separately in women and men.

resultsIn the total study cohort, women had higher augmentation pressure (AP) and augmentation index (AIx), and lower carotid-femoral pulse wave velocity (cf-PWV) than men, independent of confounders (all p < 0.001). In sex-specific analyses, higher AP was associated with higher age and 24-hours systolic blood pressure (BP), and with lower heart rate in women (all p < 0.001), and with higher age and BP in men (all p < 0.001). Similarly, higher AIx was associated with higher age and BP, and lower body mass index (BMI) and heart rate in women (all p < 0.05), and with higher age in men (all p < 0.001). Higher cf-PWV correlated with higher age and BP in women (all p < 0.005), and additionally with higher heart rate and non-smoking in men (all p < 0.05). When replacing BMI with waist-hip ratio, higher waist-hip ratio was associated with higher cf-PWV in men only (p < 0.05).

conclusionsAmong subjects with overweight and obesity, AP and AIx were higher in women, and cf-PWV was higher in men. Age and 24-hours systolic BP were the main factors associated with arterial stiffness in both sexes, while measures of adiposity had little impact on arterial stiffness.

Indexed as

OverweightVascular StiffnessAdultBlood PressureFemaleHumansMaleObesityPulse Wave AnalysisYoung AdultArterial stiffnessAugmentation indexObesityPulse wave velocitySex

Identifiers

PMID37505440
PMCPMC10600283
OpenAlexW4385330467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.