Evidence map›Paper›PMID 37505439›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2023

Arterial Stiffness Associated with Sympathetic Hyperactivity in Obese Individuals with Moderate to Severe Obstructive Sleep Apnea.

Samanta Mattos, Michelle R Cunha, Márcia R S T Klein, Wille Oigman, Mario F Neves

Abstract read
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In one paragraph

Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Samanta MattosDepartment of Clinical Medicine, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.
Michelle R CunhaDepartment of Clinical Medicine, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.
Márcia R S T KleinDepartment of Applied Nutrition, Nutrition Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Wille OigmanDepartment of Clinical Medicine, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.
Mario F NevesDepartment of Clinical Medicine, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil. mariofneves@gmail.com.ORCID http://orcid.org/0000-0002-0797-572X
Universidade do Estado do Rio de Janeiro · BR

Funding

Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
Conselho Nacional de Desenvolvimento Científico e Tecnológico 307114/2017-1Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/202.628/2019
6 · The paper itself

Abstract

introductionObstructive Sleep Apnea (OSA) is a chronic disorder associated with several risk factors, and increased Body Mass Index (BMI) and waist circumference are correlated with it is severity.

aimTo evaluate vascular function, central hemodynamics, and autonomic modulation in obese individuals with moderate and severe OSA.

methodsIndividuals of both sexes, aged 40-70 years and BMI ≥ 30 and < 40 kg/m

resultsPatients (n = 76) were divided according to Apnea-Hypopnea Index (AHI): absent-mild group (AHI < 15 events/h, n = 30) and Moderate-Severe (MS) group (AHI ≥ 15 events/h, n = 46). The Low/High Frequency (LF/HF) ratio (0.81  ±  0.48 vs 1.39  ±  1.08 ms

conclusionIn this sample of obese individuals, moderate to severe OSA was associated with sympathetic hyperactivity and evidence of accelerated vascular aging with arterial stiffness and subclinical atherosclerosis.

Indexed as

Sleep Apnea, ObstructiveVascular StiffnessCarotid Intima-Media ThicknessFemaleHumansMaleObesityPulse Wave AnalysisAutonomic nervous systemCardiovascular diseasesObesityObstructive sleep apneaVascular Stiffness

Identifiers

PMID37505439
OpenAlexW4385331525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.