Evidence map›Paper›PMID 37505420›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2023

Small-volume tubes to reduce anemia and transfusion (STRATUS): a pilot study.

Deborah M Siegal, Emilie P Belley-Côté, Shun Fu Lee, Tara Robertson, Stephen Hill, Pamela Benoit, Brandi Meeks, Julian Owen, Tanya Roglich, Elena Zotova and 1 more

Registry-linked trialOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03284944 (Small-Volume Tubes to Reduce Anemia and Transfusion), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03284944 completednot on this map

Small-Volume Tubes to Reduce Anemia and Transfusion (STRATUS): A Pilot Study

TypeobservationalSponsorPopulation Health Research InstituteRan2017 to 2018Enrolled369ConditionsBlood Loss AnemiaArmsSmall-Volume, Standard-Volume
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Deborah M SiegalDepartment of Medicine, McMaster University, Hamilton, ON, Canada. dsiegal@toh.ca.ORCID http://orcid.org/0000-0003-3806-3245
Emilie P Belley-CôtéDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Shun Fu LeeDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Tara RobertsonPopulation Health Research Institute, Hamilton, ON, Canada.
Stephen HillDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Pamela BenoitHamilton Health Sciences, Hamilton, ON, Canada.
Brandi MeeksPopulation Health Research Institute, Hamilton, ON, Canada.
Julian OwenDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Tanya RoglichHamilton Health Sciences, Hamilton, ON, Canada.
Elena ZotovaPopulation Health Research Institute, Hamilton, ON, Canada.
Stuart J ConnollyDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Population Health Research Institute · CAHamilton Health Sciences · CAMcMaster University · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBlood sampling for diagnostic testing causes blood loss. Small-volume tubes have the same cost, dimensions, and blood-draw techniques as standard-volume tubes, and are compatible with laboratory equipment; however, they are not commonly used. We sought to assess the feasibility of a stepped-wedge cluster trial to determine whether small-volume tubes reduce transfusion compared with standard-volume tubes in intensive care unit (ICU) patients.

methodsWe conducted a prospective mixed-methods pilot study (before-after design) in one ICU with a six-week control period (standard-volume tubes) and a six-week intervention period (small-volume tubes). All patients admitted to the ICU were included. Feasibility was assessed as successful switch to small-volume tubes; adherence to tube size; sufficient volume for testing; user acceptance; barriers and facilitators to implementation; and 95% transfusion collection. We explored end-user acceptability using focus groups.

resultsOne hundred and sixty-five patients were included in the standard-volume and 204 in the small-volume periods. Transition to small-volume tubes was successful. Random audits showed 100% compliance. The proportion of samples with inadequate volume for testing was the same for both groups (both, 0.2%). Based on ten focus groups, small-volume tubes were acceptable with no barriers identified. Transfusion data collection was 100%. Median [interquartile range] estimated blood loss due to laboratory testing per patient per day in ICU was 11 [8-17] mL with standard-volume and 6 [4-8] mL with small-volume tubes.

conclusionSmall-volume tubes can be implemented with acceptability to end-users and without barriers. They did not result in an increased frequency of inadequate samples. These results inform a trial to determine whether small-volume tubes reduce transfusion. STUDY REGISTRATION: ClinicalTrials.gov (NCT03284944); registered 15 September 2017.

Indexed as

AnemiaIntensive Care UnitsHumansPhlebotomyPilot ProjectsProspective Studiesanemiacritical carelaboratory testingtransfusion

Identifiers

PMID37505420
OpenAlexW4385331505

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.