Evidence map›Paper›PMID 37505394›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2023

Differences in Coronavirus disease - 19 vaccination related side effects in patients with ulcerative colitis and Crohn's disease in Japan.

Haruka Miyazaki, Daisuke Watanabe, Yuki Ito, Sayaka Ikeda, Norihiro Okamoto, Eri Tokunaga, Yuna Ku, Makoto Ooi, Namiko Hoshi, Yuzo Kodama

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Haruka MiyazakiKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0001-5155-0086
Daisuke WatanabeKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan. daisuke@med.kobe-u.ac.jp.ORCID 0000-0002-3658-5704
Yuki ItoKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0003-2068-3569
Sayaka IkedaKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0002-6184-9740
Norihiro OkamotoKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0002-0159-6171
Eri TokunagaKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0001-5165-0351
Yuna KuKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0003-3227-2556
Makoto OoiKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0002-8238-7792
Namiko HoshiKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0003-2768-3991
Yuzo KodamaKobe University Graduate School of Medicine, Division of Gastroenterology, Department of Internal Medicine, 7-5-1 Kusunoki Cho, Chuo Ku, Kobe, 650-0017, Japan.ORCID 0000-0003-1223-7147
Kobe University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purpose of this studyIt has been recommended that individuals with inflammatory bowel disease (IBD) be vaccinated against Coronavirus disease - 19 (COVID-19). Recently, we documented the incidence of side effects (SEs) after COVID-19 immunization among individuals with IBD in Japan. However, the study did not show differences between the types of IBD or the patients' clinical backgrounds. In this survey, we aimed at investigating whether the frequency of SEs differed among patients with IBD.

methodsA cross-sectional survey was conducted among adult patients with IBD at Kobe University between March 2022 and September 2022.

resultsTotal 195 patients, including 134 with ulcerative colitis (UC) and 61 with Crohn's disease (CD), completed the questionnaire and were included in the analysis. Of these, 92.3%, 91.3% and 44.1% received the initial, second and third dose of the COVID-19 vaccine, respectively. The frequency of local symptoms following the initial, second and third dose of the vaccine was comparable between patients with UC and CD (69.6% vs. 72.7%, 64.2% vs. 69.1% and 63.5% vs. 73.9%, respectively). Muscle pain after the initial and second doses of the COVID-19 vaccine was more common among patients treated with corticosteroids (58.1% vs. 37.6% and 60.0% vs. 31.8%, p < 0.05). Female sex, younger age and current or former smoking were associated with an increased incidence of fever or chills after the initial dose of the vaccine (p < 0.05). In contrast, corticosteroid use was identified as a factor associated with an increased incidence of muscle pain after the initial dose of vaccine (p < 0.05).

conclusionThe use of corticosteroids could increase the risk of muscle pain following COVID-19 vaccination. Additionally, factors such as female sex, younger age and current or former smoking can affect the incidence of fever or chills. This information should encourage patients with IBD to get vaccinated against COVID-19.

Indexed as

Colitis, UlcerativeCoronavirusCOVID-19COVID-19 VaccinesCrohn DiseaseInflammatory Bowel DiseasesAdrenal Cortex HormonesAdultCross-Sectional StudiesFemaleHumansJapanMyalgiaVaccinationAdrenal Cortex HormonesCOVID-19 VaccinesAdrenal cortex hormonesCOVID-19Crohn’s diseaseDrug-related side effects and adverse reactionsInflammatory bowel diseasesMyalgiaSARS-CoV-2Surveys and questionnairesUlcerative colitisVaccines

Identifiers

PMID37505394
OpenAlexW4385330993

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.