Evidence map›Paper›PMID 37504944›Full record

ArticleMarine drugs2023

Case Studies in Molecular Network-Guided Marine Biodiscovery.

Shamsunnahar Khushi, Angela A Salim, Robert J Capon

Abstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shamsunnahar KhushiInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.
Angela A SalimInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-8177-5689
Robert J CaponInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-8341-7754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In reviewing a selection of recent case studies from our laboratory, we revealed some lessons learned and benefits accrued from the application of mass spectrometry (MS/MS) molecular networking in the field of marine sponge natural products. Molecular networking proved pivotal to our discovery of many new natural products and even new classes of natural product, some of which were opaque to alternate dereplication and prioritization strategies. Case studies included the discovery of: (i) trachycladindoles, an exceptionally rare class of bioactive indole alkaloid previously only known from a single southern Australia sample of

Indexed as

Biological ProductsPoriferaAnimalsIndole AlkaloidsSesterterpenesTandem Mass SpectrometryBiological ProductsIndole AlkaloidsSesterterpenesglobal natural products social molecular networkingGNPSmarine natural products

Identifiers

PMID37504944
PMCPMC10381900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.