Evidence map›Paper›PMID 37504935›Full record

ArticleMarine drugs2023

Enhanced Expression of p53 and Suppression of PI3K/Akt/mTOR by Three Red Sea Algal Extracts: Insights on Their Composition by LC-MS-Based Metabolic Profiling and Molecular Networking.

Nouran M Fahmy, Mariam I Gamal El-Din, Maha M Salem, Sarah H Rashedy, Gyu Sung Lee, Yoon Seo Jang, Ki Hyun Kim, Chung Sub Kim, Mohamed El-Shazly, Shaimaa Fayez

Abstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. New insights into the anticancer effects ofFrontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nouran M FahmyDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo 11566, Egypt.ORCID 0000-0003-0052-5096
Mariam I Gamal El-DinDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo 11566, Egypt.
Maha M SalemBiochemistry Division, Chemistry Department, Faculty of Science, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-9108-6932
Sarah H RashedyNational Institute of Oceanography and Fisheries (NIOF), Cairo 11516, Egypt.ORCID 0000-0001-8531-4719
Gyu Sung LeeDepartment of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Yoon Seo JangSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-5285-9138
Chung Sub KimDepartment of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0001-9961-4093
Mohamed El-ShazlyDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo 11566, Egypt.
Shaimaa FayezDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo 11566, Egypt.

Funding

National Research Foundation of Korea No. 2022R1A6A1A03054419
6 · The paper itself

Abstract

Brown algae comprise up to 2000 species with wide dissemination in temperate zones. A comprehensive untargeted metabolic profiling guided by molecular networking of three uninvestigated Red-Sea-derived brown algae, namely

Indexed as

Proto-Oncogene Proteins c-aktSignal TransductionApoptosisCell Line, TumorCell ProliferationChromatography, LiquidHumansIndian OceanMCF-7 CellsPhosphatidylinositol 3-KinasesTandem Mass SpectrometryTOR Serine-Threonine KinasesTumor Suppressor Protein p53Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesTumor Suppressor Protein p53apoptosisbrown algaecytotoxicityHR-LC/MS/MSPI3K/Akt/mTORprotein kinases

Identifiers

PMID37504935
PMCPMC10381385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.