Evidence map›Paper›PMID 37504868›Full record

ReviewJournal of functional biomaterials2023

Bubble-Based Drug Delivery Systems: Next-Generation Diagnosis to Therapy.

Mihaela Kancheva, Lauren Aronson, Tara Pattilachan, Francesco Sautto, Benjamin Daines, Donald Thommes, Angela Shar, Mehdi Razavi

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Modifications of Nanobubble Therapy for Cancer Treatment.International journal of molecular sciences · 2024
    Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mihaela KanchevaCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Lauren AronsonCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Tara PattilachanBiionix (Bionic Materials, Implants & Interfaces) Cluster, Department of Medicine, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Francesco SauttoCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.ORCID 0009-0002-2530-6324
Benjamin DainesCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Donald ThommesCollege of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Angela SharBiionix (Bionic Materials, Implants & Interfaces) Cluster, Department of Medicine, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Mehdi RazaviBiionix (Bionic Materials, Implants & Interfaces) Cluster, Department of Medicine, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current radiologic and medication administration is systematic and has widespread side effects; however, the administration of microbubbles and nanobubbles (MNBs) has the possibility to provide therapeutic and diagnostic information without the same ramifications. Microbubbles (MBs), for instance, have been used for ultrasound (US) imaging due to their ability to remain in vessels when exposed to ultrasonic waves. On the other hand, nanobubbles (NBs) can be used for further therapeutic benefits, including chronic treatments for osteoporosis and cancer, gene delivery, and treatment for acute conditions, such as brain infections and urinary tract infections (UTIs). Clinical trials are also being conducted for different administrations and utilizations of MNBs. Overall, there are large horizons for the benefits of MNBs in radiology, general medicine, surgery, and many more medical applications. As such, this review aims to evaluate the most recent publications from 2016 to 2022 to report the current uses and innovations for MNBs.

Indexed as

drug delivery systemsgene delivery systemsimagingmicrobubblesnanobubbles

Identifiers

PMID37504868
PMCPMC10382061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.