Evidence map›Paper›PMID 37504863›Full record

ArticleJournal of functional biomaterials2023

Antibacterial and Antihemolytic Activity of New Biomaterial Based on Glycyrrhizic Acid and Quercetin (GAQ) against

Ewa Olchowik-Grabarek, Krzysztof Czerkas, Alimjon Davletboevich Matchanov, Rahmat Sulton Esanov, Umarbek Davlatboevich Matchanov, Maria Zamaraeva, Szymon Sekowski

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ewa Olchowik-GrabarekLaboratory of Molecular Biophysics, Department of Microbiology and Biotechnology, Faculty of Biology, University of Bialystok, 15-254 Bialystok, Poland.
Krzysztof CzerkasLaboratory of Molecular Biophysics, Department of Microbiology and Biotechnology, Faculty of Biology, University of Bialystok, 15-254 Bialystok, Poland.
Alimjon Davletboevich MatchanovInstitute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent 100143, Uzbekistan.ORCID 0000-0002-4176-3990
Rahmat Sulton EsanovInstitute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent 100143, Uzbekistan.
Umarbek Davlatboevich MatchanovInstitute of Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent 100170, Uzbekistan.
Maria ZamaraevaLaboratory of Molecular Biophysics, Department of Microbiology and Biotechnology, Faculty of Biology, University of Bialystok, 15-254 Bialystok, Poland.
Szymon SekowskiLaboratory of Molecular Biophysics, Department of Microbiology and Biotechnology, Faculty of Biology, University of Bialystok, 15-254 Bialystok, Poland.
University of Białystok · PLAcademy of Sciences Republic of Uzbekistan · UZNational University of Uzbekistan · UZYunusov Institute of the Chemistry of Plant Substances · UZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this study is to obtain and characterize the complex of quercetin with glycyrrhizic acid, which is known to serve as a drug delivery system. Quercetin is a flavonoid with a wide range of biological activities, including an antimicrobial effect. However, quercetin instability and low bioavailability that limits its use in medical practice makes it necessary to look for new nanoformulations of it. The formation of the GAQ complex (2:1) was confirmed by using UV and FT-IR spectroscopies. It was found that the GAQ exhibited antimicrobial and antihemolytical activities against

Indexed as

erythrocytesglycyrrhizic acidmembrane fluidityquercetinStaphylococcus aureusα-hemolysin

Identifiers

PMID37504863
PMCPMC10381813
OpenAlexW4384300052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.