Evidence map›Paper›PMID 37504856›Full record

ArticleJournal of functional biomaterials2023

Human Whole Blood Interactions with Craniomaxillofacial Reconstruction Materials: Exploring In Vitro the Role of Blood Cascades and Leukocytes in Early Healing Events.

Viviana R Lopes, Ulrik Birgersson, Vivek Anand Manivel, Gry Hulsart-Billström, Sara Gallinetti, Conrado Aparicio, Jaan Hong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Viviana R LopesOssDsign AB, SE-754 50 Uppsala, Sweden.ORCID 0000-0003-2079-4170
Ulrik BirgerssonDepartment of Clinical Science, Intervention and Technology, Division of Imaging and Technology, Karolinska Institute, SE-141 52 Huddinge, Sweden.ORCID 0000-0002-7983-925X
Vivek Anand ManivelRudbeck Laboratory, Department of Immunology, Genetics and Pathology (IGP), Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0002-6746-7372
Gry Hulsart-BillströmDepartment of Medicinal Chemistry, Translational Imaging, Uppsala University, SE-751 83 Uppsala, Sweden.ORCID 0000-0003-2422-831X
Sara GallinettiOssDsign AB, SE-754 50 Uppsala, Sweden.
Conrado AparicioFaculty of Odontology, UIC Barcelona-International University of Catalonia, 08195 Barcelona, Spain.ORCID 0000-0003-2969-6067
Jaan HongRudbeck Laboratory, Department of Immunology, Genetics and Pathology (IGP), Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0003-3325-6793
Uppsala University · SEKarolinska University Hospital · SEUniversitat Internacional de Catalunya · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study investigated early interactions between three alloplastic materials (calcium phosphate (CaP), titanium alloy (Ti), and polyetheretherketone (PEEK) with human whole blood using an established in vitro slide chamber model. After 60 min of contact with blood, coagulation (thrombin-antithrombin complexes, TAT) was initiated on all test materials (Ti > PEEK > CaP), with a significant increase only for Ti. All materials showed increased contact activation, with the KK-AT complex significantly increasing for CaP (

Indexed as

biomaterialscalcium phosphatecoagulationcomplementhuman whole blood

Identifiers

PMID37504856
PMCPMC10381968
OpenAlexW4384036990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.