Evidence map›Paper›PMID 37504843›Full record

ArticleJournal of functional biomaterials2023

Neuroprotective Effect of Platinum Nanoparticles Is Not Associated with Their Accumulation in the Brain of Rats.

Alexander Gennadievich Filippov, Valery Vasil'evich Alexandrin, Alexander Vladimirovich Ivanov, Alexander Alexandrovich Paltsyn, Nadezhda Borisovna Sviridkina, Edward Danielevich Virus, Polina Olegovna Bulgakova, Joanna Petrovna Burmiy, Aslan Amirkhanovich Kubatiev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Nano-structured strategies in combatting neurodegeneration.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alexander Gennadievich FilippovInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.
Valery Vasil'evich AlexandrinInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.
Alexander Vladimirovich IvanovInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.ORCID 0000-0002-2424-6115
Alexander Alexandrovich PaltsynInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.
Nadezhda Borisovna SviridkinaInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.
Edward Danielevich VirusInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.ORCID 0000-0001-9371-6494
Polina Olegovna BulgakovaInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.
Joanna Petrovna BurmiyInstitute of Microelectronic Technology and Ultra-High-Purity Materials, Akademika Osip'yana Str., 6, 142432 Chernogolovka, Russia.
Aslan Amirkhanovich KubatievInstitute of General Pathology and Pathophysiology, Baltiyskaya St., 8, 125315 Moscow, Russia.
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUInstitute of Microelectronics Technology and High Purity Materials · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platinum nanoparticles (nPts) have neuroprotective/antioxidant properties, but the mechanisms of their action in cerebrovascular disease remain unclear. We investigated the brain bioavailability of nPts and their effects on brain damage, cerebral blood flow (CBF), and development of brain and systemic oxidative stress (OS) in a model of cerebral ischemia (hemorrhage + temporary bilateral common carotid artery occlusion, tBCAO) in rats. The nPts (0.04 g/L, 3 ± 1 nm diameter) were administered to rats (

Indexed as

aminothiolscerebral blood flowcerebral ischemiacysteineglutathionehomocysteineplatinum nanoparticlesratS-adenosylhomocysteineS-adenosylmethionine

Identifiers

PMID37504843
PMCPMC10381480
OpenAlexW4382775130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.