Evidence map›Paper›PMID 37504541›Full record

ArticleJournal of cardiovascular development and disease2023

Long-Term Physical Activity Effectively Reduces the Consumption of Antihypertensive Drugs: A Randomized Controlled Trial.

Alessandra di Cagno, Giovanni Fiorilli, Andrea Buonsenso, Giulia Di Martino, Marco Centorbi, Antonella Angiolillo, Giuseppe Calcagno, Klara Komici, Alfonso Di Costanzo

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandra di CagnoDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
Giovanni FiorilliDepartment of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-3786-7818
Andrea BuonsensoDepartment of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-2560-5789
Giulia Di MartinoDepartment of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-1468-7491
Marco CentorbiDepartment of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0001-6188-1137
Antonella AngiolilloCentre for Research and Training in Medicine of Aging, Department of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-0158-3039
Giuseppe CalcagnoDepartment of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-4680-1535
Klara KomiciCentre for Research and Training in Medicine of Aging, Department of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0001-9419-2426
Alfonso Di CostanzoCentre for Research and Training in Medicine of Aging, Department of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-6138-5640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough physical activity (PA) has been shown to enhance hypertension control, the impact of exercise on the potential decrease of the use of antihypertensive medications remains inadequately researched.

aimThe aim was to assess the impact of a two-year PA on the medication requirements of individuals with hypertension.

methodsA clinical trial was conducted, involving 130 participants with essential hypertension who took at least one antihypertensive medication. Participants were randomly assigned to either a control group (CG

resultsA total of 76 participants completed the 24-month assessment, and RM-ANOVA revealed a significantly lower antihypertensive drug load in the EG compared to the CG at 18 (

conclusionA long-term PA program can decrease the antihypertensive drug load in older adults with essential hypertension. The trend of improvement regarding the EG drug load intake and the trend of CG drug load increase, although not significant over time, results in a significant difference between the groups at 18 months and an even greater difference at 24 months. This trend certifies the protective value of PA against the aging process and its related health risk factors.

Indexed as

antihypertensive drug loadblood pressureexercise

Identifiers

PMID37504541
PMCPMC10380464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.