Evidence map›Paper›PMID 37504402›Full record

ReviewGels (Basel, Switzerland)2023

Polymer-Based Hydrogels Applied in Drug Delivery: An Overview.

Nguyen Hoc Thang, Truong Bach Chien, Dang Xuan Cuong

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 263 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
263citing papers in PubMed, 1 pooled it
60.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

263 citing papers in PubMed, 1 synthesis or guideline pooled it, 633 citations in OpenAlex.

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203 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nguyen Hoc ThangFaculty of Chemical Technology, Ho Chi Minh City University of Food Industry, 140 Le Trong Tan, Tan Phu Distrist, Ho Chi Minh City 700000, Vietnam.ORCID 0000-0002-2215-8859
Truong Bach ChienFaculty of Chemical Technology, Ho Chi Minh City University of Food Industry, 140 Le Trong Tan, Tan Phu Distrist, Ho Chi Minh City 700000, Vietnam.
Dang Xuan CuongInnovation and Entrepreneurship Center, Ho Chi Minh City University of Food Industry, 140 Le Trong Tan, Tan Phu Distrist, Ho Chi Minh City 700000, Vietnam.
Ho Chi Minh City University of Industry and Trade · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied for drug delivery applications because of their ability to hold large amounts of water and biological fluids and control drug release based on their unique physicochemical properties and biocompatibility. Current trends in the development of hydrogel drug delivery systems involve the release of drugs in response to specific triggers such as pH, temperature, or enzymes for targeted drug delivery and to reduce the potential for systemic toxicity. In addition, developing injectable hydrogel formulations that are easily used and sustain drug release during this extended time is a growing interest. Another emerging trend in hydrogel drug delivery is the synthesis of nano hydrogels and other functional substances for improving targeted drug loading and release efficacy. Following these development trends, advanced hydrogels possessing mechanically improved properties, controlled release rates, and biocompatibility is developing as a focus of the field. More complex drug delivery systems such as multi-drug delivery and combination therapies will be developed based on these advancements. In addition, polymer-based hydrogels are gaining increasing attention in personalized medicine because of their ability to be tailored to a specific patient, for example, drug release rates, drug combinations, target-specific drug delivery, improvement of disease treatment effectiveness, and healthcare cost reduction. Overall, hydrogel application is advancing rapidly, towards more efficient and effective drug delivery systems in the future.

Indexed as

biopolymersdrug deliveryhydrogelsmulti-sensitive hydrogelsnanoparticles

Identifiers

PMID37504402
PMCPMC10379988
OpenAlexW4382584043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.