Evidence map›Paper›PMID 37504360›Full record

ReviewCurrent oncology (Toronto, Ont.)2023

Cancer Pain Management: A Narrative Review of Current Concepts, Strategies, and Techniques.

François Mestdagh, Arnaud Steyaert, Patricia Lavand'homme

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07408193 (The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain), which is not on this map. Cited by 120 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 10 pooled it
57.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07408193 early_phase1recruitingnot on this mapstarted 2026, after this paper: background citation

The Role of Coadministration of Lidocaine and Ketamine in Opioid-Refractory Chronic Cancer-Related Pain: a Randomized, Double-Blinded, Placebo-Controlled, Cross-Over Trial.

TypeinterventionalSponsorNational and Kapodistrian University of AthensRan2026 to 2027Enrolled24ConditionsOpioid-Refractory Chronic Cancer-Related PainArmsLidocaine and Ketamine Infusion, Active Placebo (Midazolam) Infusion
3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 10 syntheses or guidelines pooled it, 167 citations in OpenAlex.

  1. Pooled it
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  11. [Electrotherapy and sensory re-education as a treatment for chemotherapy-induced neuropathy].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Trial
  12. Trial
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  14. Review
  15. Article
  16. Early analgesic response to interventional pain procedures in hospitalized patients with cancer-related pain: clinical predictors and exploratory survival analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  17. Article
  18. Cancer pain.Nature reviews. Disease primers · 2026
    Review
  19. Perioperative considerations for patients with multiple myeloma.European journal of anaesthesiology and intensive care · 2026
    Review
  20. [Ultrasound glossopharyngeal block for oropharyngeal pain management in cancer patients].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

François MestdaghDepartment of Anesthesiology and Pain Clinic, Cliniques Universitaires Saint Luc, University Catholic of Louvain, Av Hippocrate 10, B-1200 Brussels, Belgium.
Arnaud SteyaertDepartment of Anesthesiology and Pain Clinic, Cliniques Universitaires Saint Luc, University Catholic of Louvain, Av Hippocrate 10, B-1200 Brussels, Belgium.
Patricia Lavand'hommeDepartment of Anesthesiology and Acute Postoperative & Transitional Pain Service, Cliniques Universitaires Saint Luc, University Catholic of Louvain, Av Hippocrate 10, B-1200 Brussels, Belgium.ORCID 0000-0002-4527-2750
Cliniques Universitaires Saint-Luc · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain is frequently reported during cancer disease, and it still remains poorly controlled in 40% of patients. Recent developments in oncology have helped to better control pain. Targeted treatments may cure cancer disease and significantly increase survival. Therefore, a novel population of patients (cancer survivors) has emerged, also enduring chronic pain (27.6% moderate to severe pain). The present review discusses the different options currently available to manage pain in (former) cancer patients in light of progress made in the last decade. Major progress in the field includes the recent development of a chronic cancer pain taxonomy now included in the International Classification of Diseases (ICD-11) and the update of the WHO analgesic ladder. Until recently, cancer pain management has mostly relied on pharmacotherapy, with opioids being considered as the mainstay. The opioids crisis has prompted the reassessment of opioids use in cancer patients and survivors. This review focuses on the current utilization of opioids, the neuropathic pain component often neglected, and the techniques and non-pharmacological strategies available which help to personalize patient treatment. Cancer pain management is now closer to the management of chronic non-cancer pain, i.e., "an integrative and supportive pain care" aiming to improve patient's quality of life.

Indexed as

Cancer PainChronic PainNeoplasmsAnalgesics, OpioidHumansPain ManagementQuality of LifeAnalgesics, Opioidcancer paincancer survivorsintegrative pain careneuropathic painnon-pharmacological treatmentsopioid analgesicsWHO analgesic ladder

Identifiers

PMID37504360
PMCPMC10378332
OpenAlexW4384823297

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.