Evidence map›Paper›PMID 37503875›Full record

Trial reportClinical cardiology2023

Iron deficiency in young basketball players: Is a 100 μg/L ferritin cut-off appropriate for iron supplementation?: Results of a randomized placebo-controlled study.

Emese Csulak, Titanilla Takács, Brigitta Babis, Laura Horváth, Petra Márton, Bálint Lakatos, Attila Kovács, Levente Staub, Liliána Erzsébet Szabó, Zsófia Dohy and 3 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Iron Deficiency in Athletes.Biological trace element research · 2026
    Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Emese CsulakHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0001-7683-8000
Titanilla TakácsHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Brigitta BabisHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0002-4536-8891
Laura HorváthDepartment of Internal Medicine and Hematology, Semmelweis University, Budapest, Hungary.
Petra MártonHonvéd Basketball Academy, Budapest, Hungary.
Bálint LakatosHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0002-7627-5620
Attila KovácsHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0003-2320-6434
Levente StaubArgus Cognitive, Inc., Lebanon, New Hampshire, USA.ORCID http://orcid.org/0000-0001-6270-719X
Liliána Erzsébet SzabóHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0002-4699-3648
Zsófia DohyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0002-0706-5179
Hajnalka VágóHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID http://orcid.org/0000-0002-3568-3572
Béla MerkelyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0001-6514-0723
Nóra SydóHeart and Vascular Center, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0001-9999-4321
Semmelweis University · HUArgus International (United States) · US

Funding

European Union RRF-2.3.1-21-2022-00004 (MILAB)Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund TKP2021-NKTAMinistry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund TKP2021-NKTA-46National Research, Development and Innovation Office K135076National Research, Development and Innovation Office K135076 to B.M.Thematic Excellence Programme (2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology in Hungary NKFIH-1277-2/2020
6 · The paper itself

Abstract

backgroundIron deficiency (ID) is one of the most common factors that may reduce sports performance, supplementation forms and doses are still not standardized in athletes. Our aim was to assess the iron status of young male basketball players and to study the effect of iron supplementation in a randomized placebo-controlled study. HYPOTHESIS: We hypothesized that due to the higher iron demand of athletes, the 100 μg/L ferritin cut-off may be appropriate to determine the non-anemic ID.

methodsDuring a sports cardiology screening, questionnaires, laboratory tests, electrocardiograms, echocardiography exams, and cardiopulmonary exercise tests were performed. Athletes with ID (ferritin <100 μg/L) were randomized into iron and placebo groups. Ferrous sulfate (containing 100 mg elemental iron [II] and 60 mg ascorbic acid) or placebo (50 mg vitamin C) was administered for 3 months. All exams were repeated after the supplementation period.

resultsWe included 65 (age 15.8 ± 1.7 years) basketball players divided into four age groups. Non-anemic ID was observed in 60 (92%) athletes. After supplementation, ferritin levels were higher in the iron group (75.5 ± 25.9 vs. 54.9 ± 10.4 μg/L, p < .01). Ferritin >100 μg/L level was achieved only in 15% of the athletes. There were no differences in performance between the groups (VO

conclusionsAs a result of the 3-month iron supplementation, the ferritin levels increased; however, only a small portion of the athletes achieved the target ferritin level, while performance improvement was not detectable.

Indexed as

BasketballIron DeficienciesAdolescentApoferritinsDietary SupplementsFerritinsHemoglobinsHumansIronMaleApoferritinsFerritinsHemoglobinsIronathletescardiopulmonary exercise testiron deficiencysports performance

Identifiers

PMID37503875
PMCPMC10540028
OpenAlexW4385331437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.