Evidence map›Paper›PMID 37503595›Full record

ArticleThoracic research and practice2023

Initial COVID-19 Severity and Long-COVID Manifestations: An Observational Analysis.

Nitin Goel, Nitesh Goyal, Sonam Spalgais, Parul Mrigpuri, Mandira Varma-Basil, Madhu Khanna, Ravishankar Nagaraja, Balakrishnan Menon, Raj Kumar

Open access · diamondAbstract read
In one paragraph

Article in Thoracic research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. B Cell Dynamics and Transitional B Cells in Long COVID.Current issues in molecular biology · 2025
    Article
  3. Article
  4. Long COVID syndrome: An unfolding enigma.The Indian journal of medical research · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nitin GoelDepartment of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Nitesh GoyalDepartment of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Sonam SpalgaisDepartment of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Parul MrigpuriDepartment of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Mandira Varma-BasilDepartment of Microbiology, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Madhu KhannaDepartment of Virology, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Ravishankar NagarajaDepartment of Biostatistics, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Balakrishnan MenonDepartment of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Raj KumarDepartment of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
University of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNew-onset or persistent symptoms beyond after 4 weeks from COVID-19 are termed "long-COVID." Whether the initial severity of COVID-19 has a bearing on the clinicoradiological manifestations of long COVID is an area of interest. MATERIAL AND

methodsWe did an observational analysis of the long-COVID patients after categorizing them based on their course of COVID-19 illness into mild, moderate, and severe groups. The clinical and radiological profile was compared across these groups.

resultsOut of 150 long-COVID patients recruited in the study, about 79% (118), 14% (22), and 7% (10) had a history of mild, moderate, and severe COVID-19, respectively. Fatigue (P = .001), breathlessness (P = .001), tachycardia (P = .002), tachypnea (P < .001), raised blood pressure (P < .001), crepitations (P = .04), hypoxia at rest (P < .001), significant desaturation in 6-minute walk test (P = .27), type 1 respiratory failure (P = .001), and type 2 respiratory failure (P = .001) were found to be significantly higher in the long-COVID patients with a history of severe COVID-19. These patients also had the highest prevalence of abnormal chest X-ray (60%) and honeycombing in computed tomography scan thorax (25%, P = .027).

conclusionThe course of long COVID bears a relationship with initial COVID-19 severity. Patients with severe COVID-19 are prone to develop more serious long-COVID manifestations.

Identifiers

PMID37503595
PMCPMC10765190
OpenAlexW4321453198

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.