Evidence map›Paper›PMID 37503236›Full record

ArticlebioRxiv : the preprint server for biology2023

Internet-connected cortical organoids for project-based stem cell and neuroscience education.

Matthew A T Elliott, Hunter E Schweiger, Ash Robbins, Samira Vera-Choqqueccota, Drew Ehrlich, Sebastian Hernandez, Kateryna Voitiuk, Jinghui Geng, Jess L Sevetson, Yohei M Rosen and 4 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Matthew A T ElliottGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Hunter E SchweigerGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Ash RobbinsGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Samira Vera-ChoqqueccotaGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Drew EhrlichGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Sebastian HernandezGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Kateryna VoitiukGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Jinghui GengGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Jess L SevetsonGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Yohei M RosenGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Mircea TeodorescuGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Nico O WagnerCollege of Arts and Sciences, University of San Francisco, San Francisco, CA, 94117, USA.
David HausslerGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
Mohammed A Mostajo-RadjiGenomics Institute, University of California Santa Cruz, Santa Cruz, CA, 95060, USA.
University of California, Santa Cruz · USUniversity of San Francisco · US

Funding

Nanoparticle Tracking Analyzer (NTA) for the Center for Live Cell GenomicsRM1HG011543 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, SALAMA, SOFIE REDA · 2021 to 2025
$12.0M
Data Resource and Administrative Coordination Center for the Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes ConsortiumU24MH132628 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI DAVID H HAUSSLER, Tomasz Nowakowski · 2023 to 2026
$7.9M
IRACDA at UCSC and CSUMBK12GM139185 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI FORSBERG, CAMILLA, HINCK, LINDSAY E · 2020 to 2024
$4.1M
UCSC Graduate Program in Genome SciencesT32HG012344 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Angela Norie Brooks, Christopher Vollmers · 2022 to 2026
$1.5M
NHGRI NIH HHS RM1 HG011543NHGRI NIH HHS T32 HG012344NIGMS NIH HHS K12 GM139185NIMH NIH HHS U24 MH132628
6 · The paper itself

Abstract

The introduction of internet-connected technologies to the classroom has the potential to revolutionize STEM education by allowing students to perform experiments in complex models that are unattainable in traditional teaching laboratories. By connecting laboratory equipment to the cloud, we introduce students to experimentation in pluripotent stem cell-derived cortical organoids in two different settings: Using microscopy to monitor organoid growth in an introductory tissue culture course, and using high density multielectrode arrays to perform neuronal stimulation and recording in an advanced neuroscience mathematics course. We demonstrate that this approach develops interest in stem cell and neuroscience in the students of both courses. All together, we propose cloud technologies as an effective and scalable approach for complex project-based university training.

Indexed as

Brain organoidsInternet-of-ThingsNeuroscienceOrganoidsStem CellsSTEM Education

Identifiers

PMID37503236
PMCPMC10369936
OpenAlexW4384400574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.