Evidence map›Paper›PMID 37503187›Full record

ArticlebioRxiv : the preprint server for biology2023

Ankyrin B Promotes Developmental Spine Regulation in the Mouse Prefrontal Cortex.

Kelsey E Murphy, Bryce W Duncan, Justin E Sperringer, Erin Y Zhang, Victoria A Haberman, Elliott V Wyatt, Patricia F Maness

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kelsey E Murphy
Bryce W Duncan
Justin E Sperringer
Erin Y Zhang
Victoria A Haberman
Elliott V Wyatt
Patricia F ManessORCID 0000-0003-2481-5610
University of North Carolina at Chapel Hill · US

Funding

Mechanisms of Developmental Spine Pruning Regulated by IgCAMs and SemaphorinsR01MH113280 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANESS, PATRICIA F · 2017 to 2021
$1.9M
Molecular Mechanisms of Developmental Spine RemodelingR56MH113280 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANESS, PATRICIA F · 2022 to 2023
$778k
NIMH NIH HHS R01 MH113280NIMH NIH HHS R56 MH113280
6 · The paper itself

Abstract

Postnatal regulation of dendritic spine formation and refinement in cortical pyramidal neurons is critical for excitatory/inhibitory balance in neocortical networks. Recent studies have identified a selective spine pruning mechanism in the mouse prefrontal cortex (PFC) mediated by class 3 Semaphorins and the L1-CAM cell adhesion molecules Neuron-glia related CAM (NrCAM), Close Homolog of L1 (CHL1), and L1. L1-CAMs bind Ankyrin B (AnkB), an actin-spectrin adaptor encoded by

Identifiers

PMID37503187
PMCPMC10369899
OpenAlexW4384037077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.