Evidence map›Paper›PMID 37503127›Full record

ArticlebioRxiv : the preprint server for biology2023

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.

Abrar Choudhury, Martha A Cady, Calixto-Hope G Lucas, Hinda Najem, Joanna J Phillips, Brisa Palikuqi, Naomi Zakimi, Tara Joseph, Janeth Ochoa Birrueta, William C Chen and 13 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 1 country.

Abrar ChoudhuryDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Martha A CadyDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Calixto-Hope G LucasDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA.
Hinda NajemDepartment of Neurological Surgery, Northwestern University, Chicago, IL, USA.
Joanna J PhillipsDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Brisa PalikuqiDepartment of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA.
Naomi ZakimiDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Tara JosephDepartment of Pediatrics, University of California San Francisco, San Francisco, CA,USA.
Janeth Ochoa BirruetaDepartment of Pediatrics, University of California San Francisco, San Francisco, CA,USA.
William C ChenDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
Nancy Ann Oberheim BushDepartment of Neurology, University of California San Francisco, San Francisco, CA, USA.
Shawn L Hervey-JumperDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Ophir D KleinDepartment of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA.
Christine M ToedebuschDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Craig M HorbinskiDepartment of Neurological Surgery, Northwestern University, Chicago, IL, USA.
Stephen T MagillDepartment of Neurological Surgery, Northwestern University, Chicago, IL, USA.
Aparna BhaduriDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, CA, USA.
Arie PerryDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
Peter J DickinsonDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Amy B HeimbergerDepartment of Neurological Surgery, Northwestern University, Chicago, IL, USA.
Alan AshworthDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Elizabeth E CrouchDepartment of Pediatrics, University of California San Francisco, San Francisco, CA,USA.
David R RaleighDepartment of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USNorthwestern University · USUniversity of California, Davis · USJohns Hopkins University · USUniversity of California, Los Angeles · US

Funding

Tissue CoreP50CA097257 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang · 2002 to 2026
$57.4M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
STINGing GBM: A First-in- Man Clinical Trial in Surgical Resectable Recurrent GBMP50CA221747 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Atique U. Ahmed · 2018 to 2026
$21.4M
Modulation of Microglia and T Cell Interactions in Malignant GliomaR01CA120813 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HEIMBERGER, AMY BETH, RAO, GANESH · 2007 to 2025
$4.7M
Understanding druggable drivers of meningioma tumorigenesisR01CA262311 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RALEIGH, DAVID R · 2021 to 2025
$2.7M
Targeting IDH mutations to improve seizure control in glioma patientsR01NS118039 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HORBINSKI, CRAIG MICHAEL, SWANSON, GEOFFREY T · 2020 to 2024
$2.2M
Interaction between Tissue Factor, Junctional Adhesion Molecule-A, and Integrin B1 to drive self-renewal in glioblastomaR01NS117104 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HORBINSKI, CRAIG MICHAEL, LATHIA, JUSTIN D. · 2020 to 2024
$1.5M
Stinging the Glioma Immune LandscapeR01NS120547 · NINDS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HEIMBERGER, AMY BETH, RAO, ARVIND · 2020 to 2023
$1.1M
Investigating the Regulation and Role of FOXM1 in Aggressive MeningiomaF30CA246808 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOUDHURY, ABRAR · 2020 to 2023
$159k
Development of a molecular diagnostic and prognostic signature for meningiomaF32CA213944 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAGILL, STEPHEN T · 2017 to 2017
$63k
NCI NIH HHS F30 CA246808NCI NIH HHS F32 CA213944NCI NIH HHS P50 CA097257NCI NIH HHS P50 CA221747NCI NIH HHS R01 CA120813NCI NIH HHS R01 CA262311NIGMS NIH HHS T32 GM007618NINDS NIH HHS R01 NS117104NINDS NIH HHS R01 NS118039NINDS NIH HHS R01 NS120547
6 · The paper itself

Abstract

Meningiomas are the most common primary intracranial tumors

Identifiers

PMID37503127
PMCPMC10369862
OpenAlexW4384037844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.