Evidence map›Paper›PMID 37503059›Full record

ArticlebioRxiv : the preprint server for biology2023

An mTOR/RNA pol I axis shapes chromatin architecture in response to fasting.

Nada Al-Refaie, Francesco Padovani, Francesca Binando, Johanna Hornung, Qiuxia Zhao, Benjamin D Towbin, Elif Sarinay Cenik, Nicholas Stroustrup, Kurt M Schmoller, Daphne S Cabianca

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Nada Al-Refaie
Francesco PadovaniORCID 0000-0003-2540-8240
Francesca Binando
Johanna Hornung
Qiuxia Zhao
Benjamin D TowbinORCID 0000-0001-7046-1257
Elif Sarinay CenikORCID 0000-0001-8514-5505
Nicholas StroustrupORCID 0000-0001-9530-7301
Daphne S CabiancaORCID 0000-0002-1834-7868

Funding

Role of Nucleolus and Ribosomes in Organismal Growth and HomeostasisR35GM138340 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Elif Sarinay Cenik · 2020 to 2026
$2.4M
NIGMS NIH HHS R35 GM138340
6 · The paper itself

Abstract

Chromatin architecture is a fundamental mediator of genome function. Fasting is a major environmental cue across the animal kingdom. Yet, how it impacts on 3D genome organization is unknown. Here, we show that fasting induces a reversible and large-scale spatial reorganization of chromatin in

Identifiers

PMID37503059
PMCPMC10370172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.