Evidence map›Paper›PMID 37503042›Full record

ArticlebioRxiv : the preprint server for biology2023

Novel insights into hippocampal perfusion using high-resolution, multi-modal 7T MRI.

Roy A M Haast, Sriranga Kashyap, Dimo Ivanov, Mohamed D Yousif, Jordan DeKraker, Benedikt A Poser, Ali R Khan

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Roy A M HaastCentre of Functional and Metabolic Mapping, Western University, London, Ontario, Canada.
Sriranga KashyapDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.
Dimo IvanovDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.
Mohamed D YousifCentre of Functional and Metabolic Mapping, Western University, London, Ontario, Canada.
Jordan DeKrakerMontreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Benedikt A PoserDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.
Ali R KhanCentre of Functional and Metabolic Mapping, Western University, London, Ontario, Canada.

Funding

Foundations of MRI Corticography for mesoscale organization and neuronal circuitryR01MH111444 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI FEINBERG, DAVID ALAN · 2016 to 2020
$5.1M
NIMH NIH HHS R01 MH111444
6 · The paper itself

Abstract

We present a comprehensive study on the non-invasive measurement of hippocampal perfusion. Using high-resolution 7 Tesla arterial spin labelling data, we generated robust perfusion maps and observed significant variations in perfusion among hippocampal subfields, with CA1 exhibiting the lowest perfusion levels. Notably, these perfusion differences were robust and detectable even within five minutes and just fifty perfusion-weighted images per subject. To understand the underlying factors, we examined the influence of image quality metrics, various tissue microstructure and morphometry properties, macrovasculature and cytoarchitecture. We observed higher perfusion in regions located closer to arteries, demonstrating the influence of vascular proximity on hippocampal perfusion. Moreover,

Identifiers

PMID37503042
PMCPMC10370151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.